SCHEMBL218144

SCHEMBL218144

CCC1=C(C)c2ccccc2[CH]1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAP2K7 O14733 1/20 0.33
S100A4 P26447 1/20 0.33
CDC25A P30304 1/20 0.33
CDC25B P30305 1/20 0.33
SETD7 Q8WTS6 1/20 0.33
TP53 P04637 2/20 0.32
LMNA P02545 5/20 0.31
TSHR P16473 2/20 0.31
CYP1A2 P05177 2/20 0.31
CYP2D6 P10635 2/20 0.31
ACHE P22303 2/20 0.31
ALOX15 P16050 2/20 0.31
ALOX12 P18054 1/20 0.31
RET P07949 1/20 0.31
CHRM2 P08172 1/20 0.31
HTR1A P08908 1/20 0.31
CHRM1 P11229 1/20 0.31
DRD2 P14416 1/20 0.31
ADRA2C P18825 1/20 0.31
CHRM3 P20309 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL217321 0.83 NR1H2 (0.33) MAP2K7S100A4CDC25ACDC25BSETD7
SCHEMBL217391 0.80 NR1H2 (0.37) SETD7CYP2D6ACHECYP3A4BCHE
SCHEMBL2863610 0.78 FGFR1 (0.34) SETD7TP53LMNATSHRCYP1A2
SCHEMBL61525 0.77 MEN1 (0.39) S100A4CDC25ACDC25BTP53LMNA
SCHEMBL5691590 0.76 PDCD1 (0.39) LMNATSHRCYP1A2CYP3A4ALDH1A1
SCHEMBL28066453 0.76 MEN1 (0.35) MAP2K7S100A4CDC25ACDC25BLMNA
SCHEMBL28330077 0.75 MEN1 (0.38) MAP2K7S100A4CDC25ACDC25BTP53
SCHEMBL27272943 0.75 MEN1 (0.38) MAP2K7S100A4CDC25ACDC25BTP53
SCHEMBL27709736 0.75 MEN1 (0.38) MAP2K7S100A4CDC25ACDC25BTP53
SCHEMBL6912951 0.74 NPC1 (0.32) CDC25ACDC25BSETD7LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10421921-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-09-24 US disclosed
EP-1920031-B1 LUBRICANTS FROM MIXED ALPHA-OLEFIN FEEDS EXXONMOBIL CHEMICAL PATENTS INC (US) 2018-01-10 EP disclosed
US-20170137737-A1 Lubricants from Mixed Alpha-Olefin Feeds EXXONMOBIL CHEMICAL PATENTS INC. 2017-05-18 US disclosed
US-9593288-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-03-14 US disclosed
US-9409834-B2 Low viscosity poly-alpha-olefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-08-09 US disclosed
US-20150252279-A1 Lubricants From Mixed Alpha-Olefin Feeds EXXONMOBIL CHEMICAL PATENTS INC. 2015-09-10 US disclosed
US-8957159-B2 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-02-17 US disclosed
US-8921291-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-12-30 US disclosed
US-20140378720-A1 Processes to Produce Polyalpha-Olefin Compositions EXXONMOBIL CHEMICAL PATENTS INC. 2014-12-25 US disclosed
EP-1910432-B1 PROCESS TO PRODUCE LOW VISCOSITY POLY-ALPHA-OLEFINS EXXONMOBIL CHEM PATENTS INC (US) 2014-11-12 EP disclosed
US-20090036725-A1 Process To Produce Polyalphaolefins EXXONMOBIL CHEMICAL PATENTS INC. 2009-02-05 US disclosed
WO-2009017953-A2 PROCESS TO PRODUCE POLYALPHAOLEFINS EXXONMOBIL CHEMICAL PATENT INC. (US) 2009-02-05 WO disclosed
US-20090005279-A1 Polyalpha-Olefin Compositions and Processes to Produce the Same EXXONMOBIL CHEMICAL PATENTS INC. 2009-01-01 US disclosed
WO-2008140875-A1 CATALYST SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-11-20 WO disclosed
US-20080287617-A1 Catalyst System For Olefin Polymerization And Polymers Produced Therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2008-11-20 US disclosed
US-20080177121-A1 Process to produce high viscosity fluids EXXONMOBIL CHEMICAL PATENTS INC. 2008-07-24 US disclosed
US-20070293640-A1 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2007-12-20 US disclosed
US-7294681-B2 Mutliple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-11-13 US disclosed
US-7223822-B2 Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-05-29 US disclosed
US-20070043248-A1 Process to produce low viscosity poly-alpha-olefins EXXONMOBIL CHEMICAL PATENTS INC. 2007-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090036725-A1 Process To Produce Polyalphaolefins KCNMA1, F10, AP2A1 MAP2K7 600/4885S100A4 4173/4885CDC25A 3688/4885
US-20070043248-A1 Process to produce low viscosity poly-alpha-olefins AP1M1, AP3D1, AP3M1 MAP2K7 1096/4885S100A4 2920/4885CDC25A 3376/4885
US-20080177121-A1 Process to produce high viscosity fluids SCO2, POLI, TAOK1 MAP2K7 2075/4885S100A4 1391/4885CDC25A 3996/4885
US-20140378720-A1 Processes to Produce Polyalpha-Olefin Compositions AP1M1, AP1S1, CCT4 MAP2K7 489/4885S100A4 2571/4885CDC25A 3082/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.