Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM3 | Q86V86 | 3/20 | 0.50 |
| ▸ | AR | P10275 | 2/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.42 |
| ▸ | CDK1 | P06493 | 2/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.42 |
| ▸ | CDK4 | P11802 | 2/20 | 0.42 |
| ▸ | CCND1 | P24385 | 2/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.42 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.42 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.42 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29655502 | 1.00 | PIM3 (0.50) | PIM3ARCCNB2CDK1CCNB1 | |
| SCHEMBL16534743 | 0.81 | PIM3 (0.48) | PIM3ARCCNB2CDK1CCNB1 | |
| SCHEMBL27935736 | 0.81 | PIM3 (0.48) | PIM3ARCCNB2CDK1CCNB1 | |
| SCHEMBL29755083 | 0.79 | AR (0.51) | PIM3ARCCNB2CDK1CCNB1 | |
| SCHEMBL27977982 | 0.79 | AR (0.51) | PIM3ARCCNB2CDK1CCNB1 | |
| SCHEMBL17877000 | 0.79 | PIM3 (0.54) | PIM3ARCCNB2CDK1CCNB1 | |
| SCHEMBL181890 | 0.79 | METAP2 (0.52) | PIM3CCNB2CDK1CCNB1CDK5 | |
| SCHEMBL29397381 | 0.79 | METAP2 (0.52) | PIM3CCNB2CDK1CCNB1CDK5 | |
| SCHEMBL28272924 | 0.79 | METAP2 (0.52) | PIM3CCNB2CDK1CCNB1CDK5 | |
| SCHEMBL29897733 | 0.78 | KIF11 (0.55) | PIM3PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113372261-B | Method for preparing 1-bromo/chloro carbazole and derivatives thereof | 中国科学院兰州化学物理研究所 | 2023-06-27 | — | — | CN | disclosed |
| CN-113620811-B | Halogenation method of aromatic compound | 中国科学院兰州化学物理研究所 | 2022-05-24 | — | — | CN | disclosed |
| CN-113620811-A | Halogenation method of aromatic compound | 中国科学院兰州化学物理研究所 | 2021-11-09 | — | — | CN | disclosed |
| CN-113372261-A | Method for preparing 1-bromine/chlorocarbazole and derivatives thereof | 中国科学院兰州化学物理研究所 | 2021-09-10 | — | — | CN | disclosed |