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Hydrochloric Acid

Hydrochloric Acid

SCHEMBL2863635

CC1=Cc2c(-c3ccccc3)cccc2C1[Zr+2](=C(c1ccccc1)c1ccccc1)C1c2cc(C(C)(C)C)ccc2-c2ccc(C(C)(C)C)cc21.[Cl-].[Cl-]

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CNR1 P21554 1/20 0.32
▸ CNR2 P34972 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2868324 0.91 — —
Hydrochloric Acid SCHEMBL2860769 0.90 ALDH1A1 (0.32) —
Hydrochloric Acid SCHEMBL2858361 0.89 AKR1C3 (0.30) —
Hydrochloric Acid SCHEMBL2872420 0.88 CNR2 (0.32) CNR2
Hydrochloric Acid SCHEMBL2867538 0.87 PDCD1 (0.31) —
Hydrochloric Acid SCHEMBL7929729 0.86 PDCD1 (0.33) —
Hydrochloric Acid SCHEMBL2861546 0.84 LMNA (0.32) —
Hydrochloric Acid SCHEMBL2869197 0.84 NPC1 (0.32) —
Hydrochloric Acid SCHEMBL2855740 0.84 NPC1 (0.31) CNR1CNR2
Hydrochloric Acid SCHEMBL30576293 0.84 NPC1 (0.31) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1964860-B1 ETHYLENE POLYMER, CATALYST FOR PRODUCTION OF ETHYLENE POLYMER, AND PROCESS FOR PRODUCTION OF ETHYLENE POLYMER TOSOH CORP (JP) 2017-07-05 — — EP disclosed
US-7838611-B2 Ethylene polymer, catalyst for ethylene polymer production, and method for producing ethylene polymer TOSOH CORPORATION (JP) 2010-11-23 — — US disclosed
US-7678866-B2 Polyethylene composition and process for producing same TOSOH CORPORATION (JP) 2010-03-16 — — US disclosed
US-20090137755-A1 ETHYLENE POLYMER, CATALYST FOR ETHYLENE POLYMER PRODUCTION, AND METHOD FOR PRODUCING ETHYLENE POLYMER TOSOH CORPORATION (JP) 2009-05-28 — — US disclosed
US-20040214953-A1 Polyethylene composition and process for producing same TOSOH CORPORATION 2004-10-28 — — US disclosed