SCHEMBL2864566

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2863645	0.91	TTK (0.56)	TTKPOLBKMT2AMEN1RECQL
	SCHEMBL2861303	0.85	TTK (0.75)	TTKPOLBKMT2AMEN1KDM4E
	SCHEMBL2868892	0.84	KMT2A (0.48)	TTKPOLBKMT2AMEN1HTT
	SCHEMBL2868379	0.81	TTK (0.47)	TTKMAPT
	SCHEMBL4334969	0.79	TTK (0.54)	TTKPOLBKMT2AMEN1KDM4E
	SCHEMBL2860243	0.79	TTK (0.50)	TTKPOLBKMT2AMEN1KDM4E
	SCHEMBL2855841	0.76	TTK (0.52)	TTKPOLBKMT2AMEN1RECQL
	SCHEMBL13635742	0.76	ALDH1A1 (0.39)	TTKALDH1A1L3MBTL1
	SCHEMBL4341417	0.76	GSK3A (0.55)	POLBKMT2AMEN1HSD17B10
	SCHEMBL2868575	0.76	POLB (0.45)	TTKPOLBKMT2ARAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.