Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | PTGIR | P43119 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | STS | P08842 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 2/20 | 0.42 |
| ▸ | NOS1 | P29475 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6634186 | 0.89 | MAPT (0.61) | HPGDLMNAL3MBTL1MAPTRAB9A | |
| SCHEMBL835108 | 0.81 | HPGD (1.00) | HPGDLMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL1755726 | 0.81 | HPGD (1.00) | HPGDLMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL5451478 | 0.80 | HPGD (0.73) | HPGDLMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL12762430 | 0.79 | LMNA (0.59) | HPGDLMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL14407930 | 0.76 | HPGD (0.66) | HPGDLMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL10872255 | 0.76 | HPGD (0.79) | HPGDLMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL114591 | 0.76 | MEN1 (0.47) | LMNAALDH1A1MAPTRAB9ANPSR1 | |
| SCHEMBL20591205 | 0.76 | HPGD (0.79) | HPGDLMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL12762443 | 0.75 | MAPT (0.54) | HPGDLMNAL3MBTL1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476699-B | Glucocorticoid receptor agonists and immunoconjugates thereof | 艾伯维公司 | 2021-10-12 | — | — | CN | disclosed |