Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | PTGIR | P43119 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | CES2 | O00748 | 2/20 | 0.55 |
| ▸ | CES1 | P23141 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 5/20 | 0.53 |
| ▸ | CA2 | P00918 | 5/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.52 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.52 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12762430 | 0.90 | LMNA (0.59) | HPGDL3MBTL1LMNAALDH1A1PTGIR | |
| P-Methoxy-Acetophenone SCHEMBL41285 | 0.88 | MAPT (0.70) | HPGDL3MBTL1LMNAALDH1A1MAPT | |
| SCHEMBL12762443 | 0.86 | MAPT (0.54) | HPGDL3MBTL1LMNAALDH1A1PTGIR | |
| P-Methoxy-Acetophenone SCHEMBL27814658 | 0.86 | MAPT (0.67) | HPGDL3MBTL1LMNAALDH1A1MAPT | |
| P-Methoxy-Acetophenone SCHEMBL27967967 | 0.86 | MAPT (0.67) | HPGDL3MBTL1LMNAALDH1A1MAPT | |
| P-Methoxy-Acetophenone SCHEMBL27841741 | 0.86 | MAPT (0.67) | HPGDL3MBTL1LMNAALDH1A1MAPT | |
| P-Methoxy-Acetophenone SCHEMBL9835038 | 0.86 | MAPT (0.67) | HPGDL3MBTL1LMNAALDH1A1MAPT | |
| SCHEMBL835108 | 0.85 | HPGD (1.00) | HPGDL3MBTL1LMNAALDH1A1MAPT | |
| SCHEMBL1755726 | 0.85 | HPGD (1.00) | HPGDL3MBTL1LMNAALDH1A1MAPT | |
| SCHEMBL6932815 | 0.85 | CA1 (0.77) | HPGDL3MBTL1LMNAALDH1A1PTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11427536-B2 | Photocatalyst-free, light-induced carbon-sulfur cross-coupling methods | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2022-08-30 | — | — | US | disclosed |
| US-10759765-B2 | Heterocyclic carboxylic acid amide ligand and applications thereof in copper catalyzed coupling reaction of aryl halogeno substitute | CE PHARM CO., LTD. (CN) | 2020-09-01 | — | — | US | disclosed |
| US-20190127337-A1 | HETEROCYCLIC CARBOXYLIC ACID AMIDE LIGAND AND APPLICATIONS THEREOF IN COPPER CATALYZED COUPLING REACTION OF ARYL HALOGENO SUBSTITUTE | CE PHARM CO., LTD. (CN) | 2019-05-02 | — | — | US | disclosed |
| US-20180370911-A1 | PHOTOCATALYST-FREE, LIGHT-INDUCED CARBON-SULFUR CROSS-COUPLING METHODS | U.S. DEPARTMENT OF ENERGY | 2018-12-27 | — | — | US | disclosed |
| WO-2017177979-A1 | HETEROCYCLIC CARBOXYLIC ACID AMIDE LIGAND AND APPLICATIONS THEREOF IN COPPER CATALYZED COUPLING REACTION OF ARYL HALOGENO SUBSTITUTE | 中国科学院上海有机化学研究所 | 2017-10-19 | — | — | WO | disclosed |
| US-20070082934-A1 | Substituted 4-aryloxy and 4-arylsulfanyl-phenyl-2-aminothiazoles as inhibitors of cell proliferation | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2007-04-12 | — | — | US | disclosed |
| WO-2005044263-A1 | SUBSTITUTED 4-ARYLOXY AND 4-ARYLSULFANYL-PHENYL-2-AMINOTHIAZOLES AS INHIBITORS OF CELL PROLIFERATION | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2005-05-19 | — | — | WO | disclosed |
| EP-0811002-B1 | BENZYLPIPERIDINES AND PIPERAZINES AS MUSCARINIC ANTAGONISTS | SCHERING CORP (US) | 2004-01-21 | — | — | EP | disclosed |
| US-6498168-B2 | CAPABLE OF ENHANCING ACETYLCHOLINE RELEASE WITH ACETYLCHOLINESTERASE INHIBITORS; TREATMENT OF ALZHEIMER'S DISEASE AND OTHER COGNITIVE DISORDERS | SCHERING CORPORATION | 2002-12-24 | — | — | US | disclosed |
| US-20020103205-A1 | Muscarinic antagonists | LOWE DEREK (US) | 2002-08-01 | — | — | US | disclosed |
| US-6288068-B1 | ADMINISTERING 1,4-DISUBSTITED PIPERIDINE DERIVATIVE; ALZHEIMER*S DISEASE, COGNITION ACTIVATORS; ANTICHOLINERGIC AGENTS | SCHERING CORPORATION | 2001-09-11 | — | — | US | disclosed |
| US-6037352-A | N-SUBSTITUTED PIPERIDINE DERIVATIVES; TREATING ALZHEIMER*S DISEASE, NERVOUS SYSTEM DISORDERS; ACETYLCHOLINESTERASE INHIBITORS | SCHERING CORPORATION (US) | 2000-03-14 | — | — | US | disclosed |
| US-5883096-A | DI-N-SUBSTITUTED PIPERAZINE DERIVATIVES; ALZHEIMER*S DISEASE, COGNITION ACTIVATORS; SYNERGISTIC MIXTURES WITH ACETYLCHOLINESTERASE INHIBITORS | SCHERING CORPORATION (US) | 1999-03-16 | — | — | US | disclosed |
| EP-0811002-A2 | BENZYLPIPERIDINES AND PIPERAZINES AS MUSCARINIC ANTAGONISTS | SCHERING CORPORATION (US) | 1997-12-10 | — | — | EP | disclosed |
| WO-1996026196-A2 | BENZYLPIPERIDINES AND PIPERAZINES AS MUSCARINIC ANTAGONISTS | SCHERING CORPORATION (US) | 1996-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180370911-A1 | PHOTOCATALYST-FREE, LIGHT-INDUCED CARBON-SULFUR CROSS-COUPLING METHODS | TST, CBS, CRY2 | HPGD 1394/4885L3MBTL1 1004/4885LMNA 4215/4885 |
| US-20190127337-A1 | HETEROCYCLIC CARBOXYLIC ACID AMIDE LIGAND AND APPLICATIONS THEREOF IN COPPER CATALYZED COUPLING REACTION OF ARYL HALOGENO SUBSTITUTE | AOC1, AOC2, AOC3 | HPGD 744/4885L3MBTL1 4182/4885LMNA 4664/4885 |
| US-10759765-B2 | Heterocyclic carboxylic acid amide ligand and applications thereof in copper catalyzed coupling reaction of aryl halogeno substitute | AOC1, AOC2, AOC3 | HPGD 744/4885L3MBTL1 4182/4885LMNA 4664/4885 |
| US-20020103205-A1 | Muscarinic antagonists | CHRM1, CHRM2, CHRM5 | HPGD 1195/4885L3MBTL1 3367/4885LMNA 3832/4885 |
| US-20070082934-A1 | Substituted 4-aryloxy and 4-arylsulfanyl-phenyl-2-aminothiazoles as inhibitors of cell proliferation | MKI67, CCNI, CDK4 | HPGD 2433/4885L3MBTL1 2111/4885LMNA 4630/4885 |
| US-11427536-B2 | Photocatalyst-free, light-induced carbon-sulfur cross-coupling methods | TST, CBS, CRY2 | HPGD 1394/4885L3MBTL1 1004/4885LMNA 4215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.