Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | ESR1 | P03372 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28716126 | 0.89 | ESR1 (0.52) | KMT2AMEN1LMNATDP1ESR1 | |
| SCHEMBL245250 | 0.86 | CA1 (0.63) | KMT2AMEN1LMNATDP1ESR1 | |
| SCHEMBL636176 | 0.84 | CES2 (0.55) | KMT2AMEN1CES2CES1LMNA | |
| SCHEMBL2500365 | 0.84 | CES2 (0.55) | KMT2AMEN1CES2CES1LMNA | |
| SCHEMBL8838298 | 0.84 | TDP1 (0.58) | KMT2AMEN1CES2CES1LMNA | |
| SCHEMBL8617188 | 0.83 | ALDH1A1 (0.66) | KMT2AMEN1LMNATDP1ESR1 | |
| SCHEMBL28268071 | 0.83 | CES2 (0.46) | KMT2AMEN1CES2CES1LMNA | |
| SCHEMBL8159484 | 0.83 | CES2 (0.53) | KMT2AMEN1CES2CES1LMNA | |
| SCHEMBL7455670 | 0.81 | ALDH1A1 (0.51) | KMT2AMEN1CES2CES1ALDH1A1 | |
| SCHEMBL3158166 | 0.81 | KMT2A (0.44) | KMT2AMEN1CES2CES1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108341814-B | JAK kinase inhibitors and uses thereof | 上海翔锦生物科技有限公司 | 2021-09-03 | — | — | CN | disclosed |