SCHEMBL636176

SCHEMBL636176

O=C(OOC(=O)c1ccc(CBr)cc1)c1ccc(CBr)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.55
CES1 P23141 1/20 0.55
LMNA P02545 2/20 0.50
F2 P00734 1/20 0.50
KMT2A Q03164 4/20 0.45
MEN1 O00255 1/20 0.45
LOXL2 Q9Y4K0 1/20 0.44
CYP4A11 Q02928 4/20 0.40
ALDH1A1 P00352 3/20 0.40
CYP4F2 P78329 3/20 0.39
TRPA1 O75762 1/20 0.39
TSHR P16473 1/20 0.39
KDM4E B2RXH2 2/20 0.38
MAPT P10636 2/20 0.38
HPGD P15428 1/20 0.38
PLK1 P53350 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A3 Q01959 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CA12 O43570 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2500365 0.86 CES2 (0.55) CES2CES1LMNAKMT2AMEN1
SCHEMBL8159484 0.84 CES2 (0.53) CES2CES1LMNAKMT2AMEN1
SCHEMBL28636737 0.84 KMT2A (0.53) CES2CES1LMNAKMT2AMEN1
SCHEMBL27571589 0.83 ALDH1A1 (0.61) CES2CES1LMNAF2KMT2A
SCHEMBL12381580 0.83 CES2 (0.52) CES2CES1LMNAKMT2AMEN1
SCHEMBL33494 0.83 LOXL2 (0.66) CES2CES1LMNAKMT2AMEN1
Bromide SCHEMBL4809006 0.81 LOXL2 (0.63) CES2CES1KMT2AMEN1LOXL2
SCHEMBL4050879 0.81 LOXL2 (0.63) CES2CES1KMT2AMEN1LOXL2
SCHEMBL2500368 0.79 CES2 (0.69) CES2CES1LMNAF2KMT2A
SCHEMBL245250 0.79 CA1 (0.63) LMNAKMT2AMEN1CYP4A11ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260002044-A1 RESIN COMPOSITION FOR SEALING MATERIAL, SEALING MATERIAL INCLUDING RESIN COMPOSITION, AND SOLID POLYMER FUEL CELL AND WATER ELECTROLYZER INCLUDING SEALING MATERIAL PANAC CO LTD (JP) 2026-01-01 US disclosed
CN-118234823-B Resin composition for sealing material, sealing material using the resin composition, and solid polymer fuel cell and water electrolysis device using the sealing material 凡纳克株式会社 2025-04-08 CN disclosed
CN-119654359-A Silicone-containing copolymer, leveling agent, coating composition, resist composition, color filter, and method for producing silicone-containing copolymer DIC株式会社 2025-03-18 CN disclosed
CN-119546660-A Silicone-containing copolymer, leveling agent, coating composition, resist composition, color filter, and method for producing silicone-containing copolymer DIC株式会社 2025-02-28 CN disclosed
EP-4498456-A1 RESIN COMPOSITION FOR SEALING MATERIAL, SEALING MATERIAL USING SAID RESIN COMPOSITION, AND SOLID POLYMER FUEL CELL AND WATER ELECTROLYSIS DEVICE USING SAID SEALING MATERIAL Panac Co., Ltd. (JP) 2025-01-29 EP disclosed
WO-2024257391-A1 RESIN COMPOSITION FOR SEALING MATERIAL, SEALING MATERIAL USING SAID RESIN COMPOSITION, AND SOLID POLYMER FUEL CELL AND WATER ELECTROLYSIS DEVICE USING SAID SEALING MATERIAL パナック株式会社 2024-12-19 WO disclosed
CN-118234823-A Resin composition for sealing material, sealing material using the resin composition, and solid polymer fuel cell and water electrolysis device using the sealing material 凡纳克株式会社 2024-06-21 CN disclosed
US-20240153687-A1 COMPOSITION HAVING MAGNETOSTRICTIVE PROPERTIES, AND CURED PRODUCT THEREOF TOHOKU UNIVERSITY (JP) 2024-05-09 US disclosed
CN-117487097-A Surface-modified carbon black, carbon black dispersion, and black resist composition DIC株式会社 2024-02-02 CN disclosed
WO-2024024441-A1 SILICONE-CONTAINING COPOLYMER, LEVELING AGENT, COATING COMPOSITION, RESIST COMPOSITION, COLOR FILTER, AND SILICONE-CONTAINING COPOLYMER PRODUCTION METHOD DIC株式会社 2024-02-01 WO disclosed
US-8716361-B2 Curable fluorine-containing resin and active-energy-ray-curable composition including the same DIC CORPORATION (JP) 2014-05-06 US disclosed
EP-2554554-A1 CURABLE FLUORINE-CONTAINING RESIN AND ACTIVE ENERGY RAY CURABLE COMPOSITION USING SAME DIC Corporation (JP) 2013-02-06 EP disclosed
US-20130012647-A1 CURABLE FLUORINE-CONTAINING RESIN AND ACTIVE-ENERGY-RAY-CURABLE COMPOSITION INCLUDING THE SAME DIC CORPORATION (JP) 2013-01-10 US disclosed
US-8288493-B2 (meth)acrylic-modified siloxane compounds SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-10-16 US disclosed
EP-2112189-B1 (Meth)acrylic-modified siloxane compounds SHINETSU CHEMICAL CO (JP) 2012-02-22 EP disclosed
US-20090270529-A1 (METH)ACRYLIC-MODIFIED SILOXANE COMPOUNDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-10-29 US disclosed
EP-2112189-A1 (Meth)acrylic-modified siloxane compounds Shin-Etsu Chemical Co., Ltd. (JP) 2009-10-28 EP disclosed
EP-0490269-B1 Graft copolymer and process for producing the same IDEMITSU KOSAN CO (JP) 1996-02-28 EP disclosed
US-5250629-A Graft polymerization of styrene and ethylenically unsaturated monomer using transition metal catalysts, organoaluminum compounds; films, packaging, automobile parts IDEMITSU KOSAN CO., LTD. (JP) 1993-10-05 US disclosed
EP-0490269-A1 Graft copolymer and process for producing the same IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-06-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090270529-A1 (METH)ACRYLIC-MODIFIED SILOXANE COMPOUNDS MMAB, MGMT, PAM CES2 833/4885CES1 3403/4885LMNA 3053/4885
US-20260002044-A1 RESIN COMPOSITION FOR SEALING MATERIAL, SEALING MATERIAL INCLUDING RESIN COMPOSITION, AND SOLID POLYMER FUEL CELL AND WATER ELECTROLYZER INCLUDING SEALING MATERIAL GJA1, ERCC1, ASH2L CES2 190/4885CES1 283/4885LMNA 110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.