Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL28636930

CCNC(=O)c1cc[n+](CC[C@H](N)C(=O)O)nc1.O=C(O)C(F)(F)F

nearest known ligand 0.33

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA5 P31644 2/20 0.33
HDAC4 P56524 2/20 0.33
HDAC6 Q9UBN7 2/20 0.33
HDAC1 Q13547 1/20 0.33
GRB2 P62993 1/20 0.33
DPP4 P27487 1/20 0.33
DPP7 Q9UHL4 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
EPHX2 P34913 2/20 0.32
PPARG P37231 2/20 0.32
PPARA Q07869 1/20 0.32
PTPN1 P18031 2/20 0.31
MAPK14 Q16539 2/20 0.31
GRM8 O00222 1/20 0.31
GRM4 Q14833 1/20 0.31
ITGB3 P05106 1/20 0.31
ITGA2B P08514 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL28636927 0.94 GABRA5 (0.33) GABRA5HDAC4HDAC6HDAC1MAPK14
SCHEMBL22018097 0.93 CASR (0.34) EPHX2MAPK14GRM8GRM4CASR
Trifluoroacetic Acid SCHEMBL21964011 0.89 HDAC4 (0.34) GABRA5HDAC4HDAC6HDAC1GRB2
Trifluoroacetic Acid SCHEMBL21964012 0.85 HDAC4 (0.32) GABRA5HDAC4HDAC6HDAC1GRB2
SCHEMBL28636921 0.85 GABRA5 (0.32) GABRA5HDAC4HDAC6HDAC1
SCHEMBL22018105 0.82 HPGDS (0.35) GABRA5MAPK14
SCHEMBL22018291 0.82 HPGDS (0.35) GABRA5MAPK14
SCHEMBL22018303 0.82 SLC7A5 (0.43) GRM8GRM4CASR
SCHEMBL22018287 0.76 KMT2A (0.35) GRM8GRM4
Trifluoroacetic Acid SCHEMBL20744300 0.76 GRB2 (0.34) GRB2DPP4DPP7PTPN1GRM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113329629-A Herbicidal compounds 先正达农作物保护股份公司 2021-08-31 CN disclosed