SCHEMBL22018287

SCHEMBL22018287

NC(=O)c1cc[n+](CCC(N)C(=O)O)nc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.35
ALOX15 P16050 1/20 0.35
BLM P54132 1/20 0.35
PMP22 Q01453 1/20 0.35
KIF11 P52732 4/20 0.35
HSD17B10 Q99714 1/20 0.34
ALDH1A1 P00352 1/20 0.33
MEN1 O00255 1/20 0.33
APAF1 O14727 1/20 0.33
RGS12 O14924 1/20 0.33
HSP90AA1 P07900 1/20 0.33
MAPK1 P28482 1/20 0.33
GRIK1 P39086 2/20 0.33
GRIA1 P42261 2/20 0.33
GRIA2 P42262 2/20 0.33
GRIA3 P42263 2/20 0.33
GRIA4 P48058 2/20 0.33
GRIK2 Q13002 2/20 0.33
GRIK3 Q13003 2/20 0.33
NOS1 P29475 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28635990 0.92 NOS1 (0.36) KMT2AKIF11MEN1APAF1RGS12
SCHEMBL22018303 0.84 SLC7A5 (0.43) KMT2AKIF11SLC7A5GRM4GRM8
SCHEMBL22018097 0.82 CASR (0.34) SLC7A5GRM4GRM8
SCHEMBL22345227 0.79 KIF11 (0.35) KIF11HSD17B10NOS1ALPIPKM
SCHEMBL22345226 0.79 KIF11 (0.35) KIF11HSD17B10NOS1ALPIPKM
SCHEMBL20753844 0.79 KIF11 (0.35) KIF11HSD17B10NOS1ALPIPKM
Trifluoroacetic Acid SCHEMBL28636930 0.76 GABRA5 (0.33) GRM4GRM8
SCHEMBL28622137 0.75 MAPK1 (0.40) KMT2AMEN1APAF1RGS12HSP90AA1
Trifluoroacetic Acid SCHEMBL28636927 0.75 GABRA5 (0.33)
Trifluoroacetic Acid SCHEMBL20743519 0.73 GRB2 (0.34) KIF11TPH1ALPIPKMPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113329629-A Herbicidal compounds 先正达农作物保护股份公司 2021-08-31 CN disclosed
WO-2020099367-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2020-05-22 WO disclosed