Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.56 |
| ▸ | AR | P10275 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | RET | P07949 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10640596 | 0.81 | CYP1A2 (0.50) | CYP3A4ARMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6601227 | 0.76 | CYP2C9 (0.42) | CYP3A4MAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL28651293 | 0.75 | ALDH1A1 (0.66) | CYP3A4ARMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9137293 | 0.74 | ALDH1A1 (0.72) | CYP3A4ARMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL29085507 | 0.73 | ALDH1A1 (0.63) | CYP3A4ARMAPTALDH1A1SMN1; SMN2 | |
| 5-Hydroxyflavone SCHEMBL2390993 | 0.72 | AR (1.00) | CYP3A4ARMAPTALDH1A1SMN1; SMN2 | |
| 5-Hydroxyflavone SCHEMBL158303 | 0.72 | AR (1.00) | CYP3A4ARMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL31303695 | 0.72 | CYP3A4 (0.67) | CYP3A4ARMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9138573 | 0.72 | CYP3A4 (0.67) | CYP3A4ARMAPTALDH1A1SMN1; SMN2 | |
| 5-Hydroxyflavone SCHEMBL30630415 | 0.72 | AR (1.00) | CYP3A4ARMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113512018-A | Flavonoid compound and preparation method and application thereof | 合肥工业大学 | 2021-10-19 | — | — | CN | disclosed |