Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 8/20 | 0.67 |
| ▸ | MAPT | P10636 | 7/20 | 0.67 |
| ▸ | TP53 | P04637 | 6/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | AR | P10275 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.67 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 5/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.66 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.60 |
| ▸ | ABCG2 | Q9UNQ0 | 7/20 | 0.60 |
| ▸ | GABRP | O00591 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31303695 | 1.00 | CYP3A4 (0.67) | CYP3A4MAPTTP53ALDH1A1AR | |
| SCHEMBL25449242 | 0.89 | AR (0.73) | CYP3A4MAPTTP53ALDH1A1AR | |
| SCHEMBL1645772 | 0.86 | AR (0.54) | CYP3A4MAPTTP53ALDH1A1AR | |
| SCHEMBL28568538 | 0.84 | CYP3A4 (0.72) | CYP3A4MAPTTP53ALDH1A1AR | |
| Flavone SCHEMBL27686205 | 0.82 | TNKS (0.84) | CYP3A4MAPTTP53ALDH1A1AR | |
| SCHEMBL1144261 | 0.81 | ABCB1 (0.74) | CYP3A4MAPTTP53ALDH1A1AR | |
| SCHEMBL31675833 | 0.81 | ABCB1 (0.74) | CYP3A4MAPTTP53ALDH1A1AR | |
| Methoxyvone SCHEMBL3409370 | 0.80 | CYP3A4 (1.00) | CYP3A4MAPTTP53ALDH1A1AR | |
| SCHEMBL12378900 | 0.80 | MAPT (0.76) | CYP3A4MAPTTP53ALDH1A1AR | |
| Methoxyvone SCHEMBL29373562 | 0.80 | CYP3A4 (1.00) | CYP3A4MAPTTP53ALDH1A1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399584-A | Preventing gastrointestinal damage caused by nonsteroidal antiinflammatory drugs | THE PROCTER & GAMBLE COMPANY (US) | 1995-03-21 | — | — | US | disclosed |