Hydrazine

Hydrazine

SCHEMBL28637669

NN.O=[N+]([O-])c1ccc2c([N+](=O)[O-])c1-2

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.45
ACHE P22303 1/20 0.45
CES1 P23141 1/20 0.45
S100A4 P26447 2/20 0.44
TSHR P16473 5/20 0.42
CYP3A4 P08684 2/20 0.42
TP53 P04637 1/20 0.42
HPGD P15428 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HIF1A Q16665 1/20 0.42
TDP1 Q9NUW8 4/20 0.41
MAPT P10636 3/20 0.41
POLB P06746 2/20 0.41
APEX1 P27695 1/20 0.41
CASP6 P55212 1/20 0.41
PTPRC P08575 1/20 0.40
GPR35 Q9HC97 1/20 0.39
KMT2A Q03164 2/20 0.39
RECQL P46063 1/20 0.39
MCL1 Q07820 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15941655 0.80 BCHE (0.37) BCHEACHECES1S100A4TSHR
Hydrazine SCHEMBL5753983 0.76 ALDH1A1 (0.44) BCHEACHECES1S100A4TSHR
SCHEMBL2832432 0.75 BCHE (0.50) BCHEACHECES1S100A4TSHR
Hydrazine SCHEMBL27667270 0.74 ALDH1A1 (0.42) BCHEACHECES1S100A4TSHR
SCHEMBL3302919 0.73 TSHR (0.56) BCHEACHECES1TSHRCYP3A4
SCHEMBL8973490 0.72 BCHE (0.53) BCHEACHECES1S100A4TSHR
SCHEMBL2825166 0.72 S100A4 (0.51) S100A4TSHRCYP3A4TP53HPGD
Urea SCHEMBL9444490 0.71 GPR35 (0.46) BCHEACHECES1TSHRCYP3A4
Hydrazine SCHEMBL28157059 0.70 TSHR (0.65) S100A4TSHRSMN1; SMN2TDP1MAPT
Methyl Alcohol SCHEMBL27689667 0.70 ALDH1A1 (0.44) BCHEACHECES1S100A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118330100-A Method for detecting 2, 4-dinitrophenylhydrazine compound and extraction head 红河学院 2024-07-12 CN disclosed
CN-214374479-U Online derivatization device for high-resolution mass spectrometry detection 郑州大学 2021-10-08 CN disclosed