Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | LTK | P29376 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.46 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.46 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.46 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 6/20 | 0.45 |
| ▸ | CCND1 | P24385 | 6/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29539083 | 0.88 | FEN1 (0.56) | ALDH1A1MAPK1FEN1DYRK1BCDK5 | |
| SCHEMBL19893738 | 0.88 | FEN1 (0.56) | ALDH1A1MAPK1FEN1DYRK1BCDK5 | |
| SCHEMBL16442655 | 0.83 | NR1H2 (0.41) | ALDH1A1MAPK1FEN1DYRK1BCDK5 | |
| SCHEMBL29655384 | 0.82 | PIM1 (0.55) | DYRK1BCDK5FGFR1KDRAURKB | |
| SCHEMBL1817707 | 0.82 | PIM1 (0.55) | DYRK1BCDK5FGFR1KDRAURKB | |
| SCHEMBL16648226 | 0.78 | L3MBTL1 (0.37) | ALDH1A1MAPK1FEN1DYRK1BCDK5 | |
| SCHEMBL25481374 | 0.78 | CDK4 (0.43) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL24037054 | 0.78 | MAP4K4 (0.48) | ALDH1A1MAPK1FEN1DYRK1BCDK5 | |
| SCHEMBL21709358 | 0.78 | CDK4 (0.56) | ALDH1A1MAPK1FEN1DYRK1BCDK5 | |
| SCHEMBL28644822 | 0.78 | CYP2A6 (0.52) | FEN1DYRK1BCDK5FGFR1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113372261-B | Method for preparing 1-bromo/chloro carbazole and derivatives thereof | 中国科学院兰州化学物理研究所 | 2023-06-27 | — | — | CN | disclosed |
| CN-113620811-B | Halogenation method of aromatic compound | 中国科学院兰州化学物理研究所 | 2022-05-24 | — | — | CN | disclosed |
| CN-113620811-A | Halogenation method of aromatic compound | 中国科学院兰州化学物理研究所 | 2021-11-09 | — | — | CN | disclosed |
| CN-113372261-A | Method for preparing 1-bromine/chlorocarbazole and derivatives thereof | 中国科学院兰州化学物理研究所 | 2021-09-10 | — | — | CN | disclosed |