SCHEMBL1817707

SCHEMBL1817707

Brc1cccc2c1[nH]c1c(Br)cccc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.55
PIM3 Q86V86 1/20 0.55
NISCH Q9Y2I1 1/20 0.48
ENPP3 O14638 1/20 0.48
ENPP1 P22413 1/20 0.48
CCNE2 O96020 1/20 0.47
CDK4 P11802 1/20 0.47
CCND1 P24385 1/20 0.47
CCNE1 P24864 1/20 0.47
CDK2 P24941 1/20 0.47
CAMK2B Q13554 1/20 0.47
CAMK2G Q13555 1/20 0.47
CAMK2D Q13557 1/20 0.47
CAMK2A Q9UQM7 1/20 0.47
KDM4E B2RXH2 1/20 0.47
HSD17B10 Q99714 1/20 0.47
DYRK1A Q13627 4/20 0.46
DYRK2 Q92630 3/20 0.46
CDK9 P50750 3/20 0.46
DYRK1B Q9Y463 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29655384 1.00 PIM1 (0.55) PIM1PIM3NISCHENPP3ENPP1
SCHEMBL19621587 0.95 PIM1 (0.61) PIM1PIM3NISCHENPP3ENPP1
SCHEMBL23702740 0.87 PDE7A (0.48) PIM1PIM3NISCHENPP3ENPP1
SCHEMBL23098920 0.85 DYRK1A (0.53) PIM1PIM3NISCHENPP3ENPP1
SCHEMBL30655964 0.84 KIF11 (0.59) PIM1PIM3CCNE2CDK4CCND1
SCHEMBL783567 0.84 KIF11 (0.59) PIM1PIM3CCNE2CDK4CCND1
SCHEMBL17722736 0.83 KIF11 (0.58) PIM1PIM3NISCHENPP3ENPP1
SCHEMBL12003837 0.82 KIF11 (0.57) PIM1PIM3CCNE2CDK4CCND1
SCHEMBL28638013 0.82 ALDH1A1 (0.52) PIM1PIM3NISCHENPP3ENPP1
SCHEMBL22457401 0.80 PARP1 (0.62) PIM1PIM3NISCHENPP3ENPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117700456-A Arylamine photocatalyst and preparation method thereof, defluorinated mono-bridged ring propeller compound, preparation method and application thereof 国科大杭州高等研究院 2024-03-15 CN claimed
EP-3806176-B1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2025-06-25 EP disclosed
CN-117700456-A Arylamine photocatalyst and preparation method thereof, defluorinated mono-bridged ring propeller compound, preparation method and application thereof 国科大杭州高等研究院 2024-03-15 CN disclosed
US-20230210004-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-06-29 US disclosed
CN-113372261-B Method for preparing 1-bromo/chloro carbazole and derivatives thereof 中国科学院兰州化学物理研究所 2023-06-27 CN disclosed
US-11588117-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2023-02-21 US disclosed
CN-111875534-B Safe and efficient preparation method of 1, 8-diformylcarbazole 烟台大学 2022-06-17 CN disclosed
CN-113620811-B Halogenation method of aromatic compound 中国科学院兰州化学物理研究所 2022-05-24 CN disclosed
EP-3494112-B1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2022-04-20 EP disclosed
US-11276825-B2 Organic molecules for use in organic devices CYNORA GMBH (DE) 2022-03-15 US disclosed
WO-2015051869-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-04-16 WO disclosed
WO-2015014434-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-02-05 WO disclosed
WO-2015014435-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-02-05 WO disclosed
WO-2014067614-A1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2014-05-08 WO disclosed
US-20140066290-A1 CATHODE CATALYST FOR AIR SECONDARY BATTERY AND AIR SECONDARY BATTERY SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-03-06 US disclosed
US-20120270141-A1 NITROGEN-CONTAINING AROMATIC COMPOUNDS AND METAL COMPLEXES MAX PLANCK GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) 2012-10-25 US disclosed
EP-2493890-A1 NITROGEN-CONTAINING AROMATIC COMPOUNDS AND METAL COMPLEXES Sumitomo Chemical Company, Limited (JP) 2012-09-05 EP disclosed
CN-101397365-B 1,8-carbazoles polymer photovoltaic material, preparation and use method thereof UNIV NANJING POSTS & TELECOMM 2011-08-03 CN disclosed
WO-2011052805-A1 NITROGEN-CONTAINING AROMATIC COMPOUNDS AND METAL COMPLEXES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-05-05 WO disclosed
CN-101397365-A 1,8-carbazoles polymer photovoltaic material, preparation and use method thereof UNIV NANJING POSTS & TELECOMM (CN) 2009-04-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120270141-A1 NITROGEN-CONTAINING AROMATIC COMPOUNDS AND METAL COMPLEXES TYR, MT-CO2, SOD1 PIM1 1247/4885PIM3 1237/4885NISCH 75/4885
US-20230210004-A1 MATERIALS FOR ELECTRONIC DEVICES EPHB3, EPHA3, EPHB4 PIM1 1473/4885PIM3 772/4885NISCH 574/4885
US-11588117-B2 Materials for electronic devices EPHB3, EPHA3, EPHB4 PIM1 1473/4885PIM3 772/4885NISCH 574/4885
US-11276825-B2 Organic molecules for use in organic devices AOX1, OR10J3, L1CAM PIM1 2440/4885PIM3 2334/4885NISCH 1597/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.