SCHEMBL29655384

SCHEMBL29655384

Brc1cccc2c1[nH]c1c(Br)cccc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.55
PIM3 Q86V86 1/20 0.55
NISCH Q9Y2I1 1/20 0.48
ENPP3 O14638 1/20 0.48
ENPP1 P22413 1/20 0.48
CCNE2 O96020 1/20 0.47
CDK4 P11802 1/20 0.47
CCND1 P24385 1/20 0.47
CCNE1 P24864 1/20 0.47
CDK2 P24941 1/20 0.47
CAMK2B Q13554 1/20 0.47
CAMK2G Q13555 1/20 0.47
CAMK2D Q13557 1/20 0.47
CAMK2A Q9UQM7 1/20 0.47
KDM4E B2RXH2 1/20 0.47
HSD17B10 Q99714 1/20 0.47
DYRK1A Q13627 4/20 0.46
DYRK2 Q92630 3/20 0.46
CDK9 P50750 3/20 0.46
DYRK1B Q9Y463 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1817707 1.00 PIM1 (0.55) PIM1PIM3NISCHENPP3ENPP1
SCHEMBL19621587 0.95 PIM1 (0.61) PIM1PIM3NISCHENPP3ENPP1
SCHEMBL23702740 0.87 PDE7A (0.48) PIM1PIM3NISCHENPP3ENPP1
SCHEMBL23098920 0.85 DYRK1A (0.53) PIM1PIM3NISCHENPP3ENPP1
SCHEMBL30655964 0.84 KIF11 (0.59) PIM1PIM3CCNE2CDK4CCND1
SCHEMBL783567 0.84 KIF11 (0.59) PIM1PIM3CCNE2CDK4CCND1
SCHEMBL17722736 0.83 KIF11 (0.58) PIM1PIM3NISCHENPP3ENPP1
SCHEMBL12003837 0.82 KIF11 (0.57) PIM1PIM3CCNE2CDK4CCND1
SCHEMBL28638013 0.82 ALDH1A1 (0.52) PIM1PIM3NISCHENPP3ENPP1
SCHEMBL22457401 0.80 PARP1 (0.62) PIM1PIM3NISCHENPP3ENPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119551663-A Preparation method of nitrogen atom doped non-benzene graphene nanoribbon with wide band gap 昆明理工大学 2025-03-04 CN claimed
CN-117700456-A Arylamine photocatalyst and preparation method thereof, defluorinated mono-bridged ring propeller compound, preparation method and application thereof 国科大杭州高等研究院 2024-03-15 CN claimed
CN-119551663-B Preparation method of nitrogen atom doped non-benzene graphene nanoribbon with wide band gap 昆明理工大学 2025-11-14 CN disclosed
CN-120118126-A Carbazole metal complex, preparation method thereof and application thereof in preparation of anti-novel coronavirus drugs 上海健康医学院 2025-06-10 CN disclosed
CN-119551663-A Preparation method of nitrogen atom doped non-benzene graphene nanoribbon with wide band gap 昆明理工大学 2025-03-04 CN disclosed
CN-119551663-A Preparation method of nitrogen atom doped non-benzene graphene nanoribbon with wide band gap 昆明理工大学 2025-03-04 CN disclosed
CN-117700456-A Arylamine photocatalyst and preparation method thereof, defluorinated mono-bridged ring propeller compound, preparation method and application thereof 国科大杭州高等研究院 2024-03-15 CN disclosed
CN-113372261-B Method for preparing 1-bromo/chloro carbazole and derivatives thereof 中国科学院兰州化学物理研究所 2023-06-27 CN disclosed
CN-111875534-B Safe and efficient preparation method of 1, 8-diformylcarbazole 烟台大学 2022-06-17 CN disclosed
CN-113620811-B Halogenation method of aromatic compound 中国科学院兰州化学物理研究所 2022-05-24 CN disclosed