Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Selenium SCHEMBL29994193 | 0.96 | BCAT2 (0.43) | BCAT2HPGDALDH1A1MAPTKDM4E | |
| SCHEMBL4137654 | 0.84 | ALDH1A1 (0.47) | HPGDALDH1A1MAPTKDM4ETSHR | |
| SCHEMBL6375180 | 0.84 | PARP1 (0.39) | BCAT2HPGDALDH1A1MAPTKDM4E | |
| SCHEMBL2422410 | 0.82 | FOLH1 (0.53) | HPGDALDH1A1MAPTKDM4ETSHR | |
| SCHEMBL5747184 | 0.82 | BTK (0.42) | BCAT2HPGDALDH1A1MAPTKDM4E | |
| SCHEMBL633639 | 0.82 | HPGD (0.39) | BCAT2HPGDALDH1A1MAPTKDM4E | |
| SCHEMBL4347735 | 0.81 | ALDH1A1 (0.42) | BCAT2HPGDALDH1A1MAPTKDM4E | |
| SCHEMBL1901533 | 0.81 | KDM4E (0.45) | BCAT2HPGDALDH1A1MAPTKDM4E | |
| SCHEMBL11388477 | 0.81 | ALDH1A1 (0.44) | HPGDALDH1A1MAPTKDM4ETSHR | |
| SCHEMBL31722804 | 0.81 | ALDH1A1 (0.44) | HPGDALDH1A1MAPTKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3030561-A1 | N-CYANOMETHYLAMIDES AS INHIBITORS OF JANUS KINASE | Cadila Healthcare Limited (IN) | 2016-06-15 | — | — | EP | claimed |
| EP-3023422-A1 | PHENYL AMINO PYRIMIDINE COMPOUNDS AND USES THEREOF | YM BioSciences Australia Pty Ltd (AU) | 2016-05-25 | — | — | EP | claimed |
| WO-2015019365-A1 | N-CYANOMETHYLAMIDES AS INHIBITORS OF JANUS KINASE | CADILA HEALTHCARE LIMITED (IN) | 2015-02-12 | — | — | WO | claimed |
| EP-2152701-A1 | PHENYL AMINO PYRIMIDINE COMPOUNDS AND USES THEREOF | Cytopia Research Pty Ltd (AU) | 2010-02-17 | — | — | EP | claimed |
| WO-2008109943-A1 | PHENYL AMINO PYRIMIDINE COMPOUNDS AND USES THEREOF | CYTOPIA RESEARCH PTY LTD (AU) | 2008-09-18 | — | — | WO | claimed |
| EP-0210893-B1 | BENZAMIDES, PROCESS FOR THEIR PREPARATION AND THEIR THERAPEUTICAL USE | Laboratoires DELAGRANGE, Société Anonyme (FR) | 1990-10-03 | — | — | EP | claimed |
| EP-0210893-A1 | Benzamides, process for their preparation and their therapeutical use | Laboratoires DELAGRANGE, Société Anonyme (FR) | 1987-02-04 | — | — | EP | claimed |
| EP-3962915-B1 | SELECTIVE LIGANDS OF HUMAN CONSTITUTIVE ANDROSTANE RECEPTOR | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR V V I (CZ) | 2024-09-04 | — | — | EP | disclosed |
| WO-2023031308-A1 | CCR2 INHIBITORS | ARTICA THERAPEUTICS B.V. (NL) | 2023-03-09 | — | — | WO | disclosed |
| US-20220388967-A1 | Phenyl Amino Pyrimidine Compounds and Uses Thereof | SIERRA ONCOLOGY, INC. (US) | 2022-12-08 | — | — | US | disclosed |
| EP-3911645-B1 | 5-MEMBERED HETEROARYL COMPOUNDS CONTAINING A HYDROXAMATE MOIETY AND THEIR USE | UNIV LILLE (FR) | 2022-12-07 | — | — | EP | disclosed |
| US-20220185822-A1 | SELECTIVE LIGANDS OF HUMAN CONSTITUTIVE ANDROSTANE RECEPTOR | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) | 2022-06-16 | — | — | US | disclosed |
| US-20220073475-A1 | 5-MEMBERED HETEROARYL COMPOUNDS CONTAINING A HYDROXAMATE MOIETY AND THEIR USE | UNIVERSITÉ PARIS CITÉ (FR) | 2022-03-10 | — | — | US | disclosed |
| EP-1891064-A1 | N-AMIDE DERIVATIVES OF 8-AZABICYCLO[3.2.1]OCT-3-YL AS CCR1 ANTAGONISTS | Laboratorios Almirall, S.A. (ES) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006133802-A1 | N-AMIDE DERIVATIVES OF 8-AZABICYCLO[3.2.1]OCT-3-YL AS CCR1 ANTAGONISTS | LABORATORIOS ALMIRALL, S.A. (ES) | 2006-12-21 | — | — | WO | disclosed |
| EP-0210893-B1 | BENZAMIDES, PROCESS FOR THEIR PREPARATION AND THEIR THERAPEUTICAL USE | Laboratoires DELAGRANGE, Société Anonyme (FR) | 1990-10-03 | — | — | EP | disclosed |
| US-4703055-A | GASTROMOTOR AGENTS; NO SIDE EFFECTS | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1987-10-27 | — | — | US | disclosed |
| US-4663481-A | BROMINATION | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-05-05 | — | — | US | disclosed |
| EP-0210893-A1 | Benzamides, process for their preparation and their therapeutical use | Laboratoires DELAGRANGE, Société Anonyme (FR) | 1987-02-04 | — | — | EP | disclosed |
| EP-0144177-A1 | Preparation of bromoacetamides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-06-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220073475-A1 | 5-MEMBERED HETEROARYL COMPOUNDS CONTAINING A HYDROXAMATE MOIETY AND THEIR USE | HDAC5, HDAC6, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | BCAT2 1426/4885HPGD 125/4885ALDH1A1 535/4885 |
| US-20220388967-A1 | Phenyl Amino Pyrimidine Compounds and Uses Thereof | JAK2, JAK1, JAK3 | BCAT2 116/4885HPGD 1481/4885ALDH1A1 2269/4885 |
| US-20220185822-A1 | SELECTIVE LIGANDS OF HUMAN CONSTITUTIVE ANDROSTANE RECEPTOR | NR1I2, NR1H2, NR1H4 | BCAT2 2250/4885HPGD 718/4885ALDH1A1 435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.