Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28666642 | 0.86 | BCAT2 (0.49) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL28460662 | 0.84 | MEN1 (0.40) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL28826085 | 0.84 | KDM4E (0.37) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL28203523 | 0.84 | KDM4E (0.37) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL14344103 | 0.82 | FOLH1 (0.53) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL28666028 | 0.82 | BCAT2 (0.45) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL28203520 | 0.81 | HMGB1 (0.38) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL2863807 | 0.81 | BCAT2 (0.46) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL3348759 | 0.78 | KDM4E (0.42) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL29394876 | 0.78 | AKR1C3 (0.50) | ALDH1A1MAPTTSHRNPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167556-A | Thio-hydantoin androgen receptor antagonist for treating cancer | 詹森药业有限公司 | 2019-08-23 | — | — | CN | claimed |
| EP-0869942-A1 | 4-((HETEROCYCLOALKYL OR HETEROAROMATIC)-SUBSTITUTED PHENYL]-2-AZETIDINONES USEFUL AS HYPOLIPIDEMIC AGENTS | SCHERING CORPORATION (US) | 1998-10-14 | — | — | EP | claimed |
| WO-1996019450-A1 | 4-[(HETEROCYCLOALKYL OR HETEROAROMATIC)-SUBSTITUTED PHENYL]-2-AZETIDINONES USEFUL AS HYPOLIPIDEMIC AGENTS | SCHERING CORPORATION (US) | 1996-06-27 | — | — | WO | claimed |
| US-12628827-B2 | Isoxazoline compounds and their use as pest control agents | PI INDUSTRIES LIMITED (IN) | 2026-05-19 | — | — | US | disclosed |
| US-20240308989-A1 | PYRAN DERIVATIVES AS CYP11A1 (CYTOCHROME P450 MONOOXYGENASE 11A1) INHIBITORS | ORION CORP (FI) | 2024-09-19 | — | — | US | disclosed |
| WO-2024149345-A1 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | PROFOUNDBIO US CO. (US) | 2024-07-18 | — | — | WO | disclosed |
| US-12030871-B2 | Pyran dervatives as CYP11A1 (cytochrome P450 monooxygenase 11A1) inhibitors | ORION CORPORATION (FI) | 2024-07-09 | — | — | US | disclosed |
| WO-2024078392-A1 | PHOSPHORAMIDATE COMPOUNDS AND USES THEREOF | ANRUI BIOMEDICAL TECHNOLOGY (GUANGZHOU) CO., LTD. (CN) | 2024-04-18 | — | — | WO | disclosed |
| US-11944099-B2 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | CORTEVA AGRISCIENCE LLC (US) | 2024-04-02 | — | — | US | disclosed |
| US-20240057604-A1 | ISOXAZOLINE COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS | PI INDUSTRIES LTD. (IN) | 2024-02-22 | — | — | US | disclosed |
| CN-218620662-U | Production device of propyzamide | 成武县晨晖环保科技有限公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-109640986-A | Thio-hydantoin androgen receptor antagonists for treating cancer | 詹森药业有限公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-106279132-A | 2, 4-imidazoline diketone heterocyclic derivative and preparation method and application thereof | 四川大学华西医院 | 2017-01-04 | — | — | CN | disclosed |
| EP-2324357-A1 | KIT USEFUL FOR DETECTING, SEPARATING AND/OR CHARACTERIZING A MOLECULE OF INTEREST | Polyintell (FR) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010029504-A1 | KIT USEFUL FOR DETECTING, SEPARATING AND/OR CHARACTERIZING A MOLECULE OF INTEREST | POLYINTELL (FR) | 2010-03-18 | — | — | WO | disclosed |
| EP-0869942-B1 | 4-((HETEROCYCLOALKYL OR HETEROAROMATIC)-SUBSTITUTED PHENYL]-2-AZETIDINONES USEFUL AS HYPOLIPIDEMIC AGENTS | SCHERING CORP (US) | 2002-02-13 | — | — | EP | disclosed |
| EP-0869942-A1 | 4-((HETEROCYCLOALKYL OR HETEROAROMATIC)-SUBSTITUTED PHENYL]-2-AZETIDINONES USEFUL AS HYPOLIPIDEMIC AGENTS | SCHERING CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| US-5656624-A | ADMINISTERING TO LOWER SERUM CHOLESTEROL LEVELS | SCHERING CORPORATION (US) | 1997-08-12 | — | — | US | disclosed |
| WO-1996019450-A1 | 4-[(HETEROCYCLOALKYL OR HETEROAROMATIC)-SUBSTITUTED PHENYL]-2-AZETIDINONES USEFUL AS HYPOLIPIDEMIC AGENTS | SCHERING CORPORATION (US) | 1996-06-27 | — | — | WO | disclosed |
| EP-0339976-A1 | Anti-tumour agents | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11944099-B2 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | ACHE, DDT, MLYCD | KDM4E 1609/4885ALDH1A1 443/4885MAPT 3431/4885 |
| US-12628827-B2 | Isoxazoline compounds and their use as pest control agents | HCN1, CBR3, SCN1B | KDM4E 2989/4885ALDH1A1 2076/4885MAPT 4835/4885 |
| US-20240057604-A1 | ISOXAZOLINE COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS | PRDX1, RDX, PRDX2 | KDM4E 1461/4885ALDH1A1 774/4885MAPT 3484/4885 |
| US-12030871-B2 | Pyran dervatives as CYP11A1 (cytochrome P450 monooxygenase 11A1) inhibitors | CYP11B1, CYP11B2, CYP4A11 | KDM4E 1773/4885ALDH1A1 133/4885MAPT 4304/4885 |
| US-20240308989-A1 | PYRAN DERIVATIVES AS CYP11A1 (CYTOCHROME P450 MONOOXYGENASE 11A1) INHIBITORS | CYP11B1, CYP11B2, CYP4A11 | KDM4E 2141/4885ALDH1A1 161/4885MAPT 4215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.