SCHEMBL28638162

SCHEMBL28638162

C=CC(=O)NC(C=C)c1ccccc1S(=O)(=O)O

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 5/20 0.37
CYP2C19 P33261 2/20 0.36
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
TSHR P16473 1/20 0.33
GSTO1 P78417 2/20 0.31
MYC P01106 1/20 0.30
ACACB O00763 1/20 0.30
TTR P02766 1/20 0.30
FABP4 P15090 1/20 0.30
CCNA2 P20248 1/20 0.30
CDK2 P24941 1/20 0.30
MAPK14 Q16539 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28643616 0.73 ZDHHC20 (0.40) TGM2
SCHEMBL2846550 0.72 MYC (0.33) TSHRMYCTTR
SCHEMBL3181729 0.71 MYC (0.35) TSHRMYCTTRFABP4CCNA2
SCHEMBL29167448 0.71 MYC (0.35) TSHRMYCTTRFABP4CCNA2
SCHEMBL6553219 0.71 MYC (0.39) TSHRMYCTTRFABP4CCNA2
SCHEMBL9282892 0.71 TTR (0.37) ALDH1A1CYP2C9TSHRMYCTTR
SCHEMBL9836285 0.71 TGM2 (0.41) TGM2CYP2C19ALDH1A1CYP3A4CYP2C9
SCHEMBL1813156 0.70 TGM2 (0.50) TGM2TTRFABP4CCNA2CDK2
SCHEMBL29588334 0.70 TGM2 (0.50) TGM2TTRFABP4CCNA2CDK2
SCHEMBL28840289 0.70 MYC (0.38) TSHRMYCTTRFABP4CCNA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113563510-B Temperature-resistant salt-resistant comb polymer fluid loss additive for drilling mud bentonite 建平天正矿业有限公司 2022-09-06 CN disclosed
CN-113563510-A Temperature-resistant salt-resistant comb polymer fluid loss additive for drilling mud bentonite 建平天正矿业有限公司 2021-10-29 CN disclosed