Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | MMP8 | P22894 | 2/20 | 0.34 |
| ▸ | MMP12 | P39900 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28030413 | 0.84 | TSHR (0.52) | TGM2TSHRACACBCYP2C19CYP3A4 | |
| SCHEMBL5471473 | 0.78 | TSHR (0.46) | TGM2TSHRACACBCYP2C19CYP3A4 | |
| SCHEMBL28415923 | 0.77 | TSHR (0.44) | TGM2TSHRACACBCYP2C19CYP3A4 | |
| Hydrochloric Acid SCHEMBL29110628 | 0.75 | TSHR (0.43) | TGM2TSHRACACBCYP2C19CYP3A4 | |
| SCHEMBL69176 | 0.75 | LMNA (0.56) | CYP2C9 | |
| SCHEMBL1330502 | 0.75 | LMNA (0.56) | CYP2C9 | |
| SCHEMBL4415392 | 0.73 | TDP1 (0.63) | TSHRACACBTDP1ALDH1A1MMP9 | |
| SCHEMBL5527681 | 0.73 | TDP1 (0.63) | TSHRACACBTDP1ALDH1A1MMP9 | |
| SCHEMBL28207649 | 0.73 | TDP1 (0.63) | TSHRACACBTDP1ALDH1A1MMP9 | |
| SCHEMBL28638162 | 0.71 | TGM2 (0.37) | TGM2TSHRACACBCYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272684-B1 | DERIVATIVES OF N-(METHYLSULPHONYLPHENYLETHYL)-2-PROPENAMIDES AND THEIR USE AS ANTIBIOTICS | ZAMBON S.p.A. (IT) | 1991-06-12 | — | — | EP | disclosed |
| EP-0272684-A2 | Derivatives of N-(methylsulphonylphenylethyl)-2-propenamides and their use as antibiotics | ZAMBON S.p.A. (IT) | 1988-06-29 | — | — | EP | disclosed |