Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | TP53 | P04637 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28659669 | 0.98 | NR1H4 (0.69) | NPC1NR1H4SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL28647323 | 0.97 | NR1H4 (0.67) | NPC1NR1H4SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL28645885 | 0.93 | NR1H4 (0.67) | NPC1NR1H4LMNARAB9ATSHR | |
| SCHEMBL30575459 | 0.93 | NR1H4 (0.67) | NPC1NR1H4LMNARAB9ATSHR | |
| SCHEMBL28925803 | 0.88 | NR1H4 (0.71) | NPC1NR1H4SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL30575481 | 0.88 | NR1H4 (0.71) | NPC1NR1H4SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL29077341 | 0.85 | SMN1; SMN2 (0.60) | NPC1SMN1; SMN2TP53ALDH1A1RAB9A | |
| SCHEMBL7828267 | 0.80 | NR1H4 (1.00) | NPC1NR1H4TP53RAB9ATHRB | |
| SCHEMBL10090793 | 0.79 | RAB9A (0.67) | NPC1SMN1; SMN2TP53ALDH1A1RAB9A | |
| SCHEMBL28645907 | 0.79 | ALDH1A1 (0.64) | NR1H4SMN1; SMN2ALDH1A1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112812077-B | Benzamide compound, preparation method thereof, pharmaceutical composition and application | 中国科学院上海药物研究所 | 2023-08-22 | — | — | CN | disclosed |
| CN-112812077-A | Benzamide compound and preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2021-05-18 | — | — | CN | disclosed |