Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 15/20 | 1.00 |
| ▸ | THRB | P10828 | 1/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.64 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.64 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4247021 | 0.89 | NR1H4 (0.80) | NR1H4THRBTP53MAPTMEN1 | |
| SCHEMBL6577705 | 0.88 | NR1H4 (0.78) | NR1H4THRBTP53MAPTMEN1 | |
| SCHEMBL4257510 | 0.86 | NR1H4 (0.76) | NR1H4THRBMAPTMEN1NPC1 | |
| SCHEMBL9306724 | 0.85 | NR1H4 (0.77) | NR1H4TP53MAPT | |
| SCHEMBL9713307 | 0.85 | NR1H4 (0.76) | NR1H4THRBTP53MAPTMEN1 | |
| SCHEMBL7824191 | 0.83 | TRPV1 (0.75) | NR1H4MEN1KMT2A | |
| SCHEMBL9165641 | 0.83 | NR1H4 (0.73) | NR1H4THRBTP53MAPTMEN1 | |
| SCHEMBL9453351 | 0.83 | NR1H4 (0.73) | NR1H4MAPTMEN1NPC1KMT2A | |
| SCHEMBL23657447 | 0.83 | NR1H4 (0.70) | NR1H4THRBTP53MAPTMEN1 | |
| SCHEMBL6580077 | 0.82 | NR1H4 (0.70) | NR1H4THRBTP53MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |