SCHEMBL28638586

SCHEMBL28638586

CC=C[Si](C=CC)(c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.35
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
LMNA P02545 1/20 0.30
TSHR P16473 1/20 0.30
ALOX12 P18054 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28631076 0.83 MAPT (0.32) MAPTESR1ESR2
SCHEMBL31054141 0.79 MAPT (0.35) MAPTESR1ESR2LMNATSHR
SCHEMBL7898054 0.77 MAPT (0.38) MAPTESR1ESR2
SCHEMBL12191041 0.77 MAPT (0.42) MAPTESR1ESR2
SCHEMBL7898055 0.77 MAPT (0.38) MAPTESR1ESR2
SCHEMBL18610644 0.75 MAPT (0.37) MAPTESR1ESR2
SCHEMBL7093586 0.73 MAPT (0.40) MAPTESR1ESR2TSHR
SCHEMBL30991843 0.72 ALDH1A1 (0.32) MAPTESR1ESR2
SCHEMBL18480444 0.72 ALDH1A1 (0.32) ESR1ESR2
SCHEMBL28498809 0.72 ALDH1A1 (0.32) MAPTESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114195947-B Star-branched ternary integrated rubber prepared by catalyzing with Shan Maokang rare earth catalyst and preparation method thereof 大连理工大学 2023-04-18 CN claimed
CN-113461865-B Star-branched rare earth rubber and preparation method thereof 大连理工大学 2022-06-21 CN claimed
CN-114195947-A Star-branched ternary integrated rubber prepared by catalysis of single scandium rare earth catalyst and preparation method thereof 大连理工大学 2022-03-18 CN claimed
CN-113461865-A Star-branched rare earth rubber and preparation method thereof 大连理工大学 2021-10-01 CN claimed
CN-114195947-B Star-branched ternary integrated rubber prepared by catalyzing with Shan Maokang rare earth catalyst and preparation method thereof 大连理工大学 2023-04-18 CN disclosed
CN-113461865-B Star-branched rare earth rubber and preparation method thereof 大连理工大学 2022-06-21 CN disclosed
CN-114195947-A Star-branched ternary integrated rubber prepared by catalysis of single scandium rare earth catalyst and preparation method thereof 大连理工大学 2022-03-18 CN disclosed
CN-113461865-A Star-branched rare earth rubber and preparation method thereof 大连理工大学 2021-10-01 CN disclosed