SCHEMBL7093586

SCHEMBL7093586

C/C=C/[Si](C)([O])c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.40
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
ALDH1A1 P00352 3/20 0.34
CYP2A6 P11509 1/20 0.33
ADH1B P00325 1/20 0.31
ADH1C P00326 1/20 0.31
ADH1A P07327 1/20 0.31
ADH7 P40394 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
TSHR P16473 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7898055 0.76 MAPT (0.38) MAPTESR1ESR2
SCHEMBL12191041 0.76 MAPT (0.42) MAPTESR1ESR2
SCHEMBL7898054 0.76 MAPT (0.38) MAPTESR1ESR2
SCHEMBL304128 0.74 MAPT (0.37) MAPTESR1ESR2ALDH1A1CYP2A6
SCHEMBL28638586 0.73 MAPT (0.35) MAPTESR1ESR2TSHR
SCHEMBL31054141 0.73 MAPT (0.35) MAPTESR1ESR2ALDH1A1TSHR
SCHEMBL18610644 0.70 MAPT (0.37) MAPTESR1ESR2
SCHEMBL28911 0.69 ESR1 (0.44) MAPTESR1ESR2ALDH1A1MEN1
SCHEMBL434194 0.69 ESR1 (0.44) MAPTESR1ESR2ALDH1A1TSHR
SCHEMBL21082152 0.69 MAPT (0.39) MAPTESR1ESR2ALDH1A1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6528557-B2 Ink containing a polyoxyalkylene glycol-polysiloxane block copolymer having optional spacer groups of given formula; multicolor ink jet printing with reduced dry time and/or intercolor bleed XEROX CORPORATION 2003-03-04 US disclosed
US-20020151619-A1 Inks comprising linear Asbs'A' block copolymers of alkylene oxide and siloxane XEROX CORPORATION 2002-10-17 US disclosed