Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 9/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | LOXL3 | P58215 | 2/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | NEK2 | P51955 | 1/20 | 0.37 |
| ▸ | AXL | P30530 | 5/20 | 0.37 |
| ▸ | MERTK | Q12866 | 5/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19259726 | 0.85 | LOXL2 (0.49) | LOXL2LOXL3AXLMERTKAOC3 | |
| SCHEMBL19259767 | 0.85 | LOXL2 (0.48) | LOXL2LOXL3AXLMERTKAOC3 | |
| SCHEMBL19259897 | 0.84 | LOXL2 (0.51) | LOXL2 | |
| SCHEMBL20983582 | 0.84 | LOXL2 (0.38) | LOXL2IRAK4AXLMERTK | |
| SCHEMBL20983564 | 0.82 | LOXL2 (0.45) | LOXL2IRAK4LOXL3 | |
| SCHEMBL19274598 | 0.79 | IRAK1 (0.46) | LOXL2IRAK4 | |
| SCHEMBL29970064 | 0.79 | IRAK1 (0.46) | LOXL2IRAK4 | |
| SCHEMBL28645865 | 0.79 | LOXL2 (0.40) | LOXL2LOXL3 | |
| SCHEMBL28644238 | 0.78 | LOXL2 (0.41) | LOXL2LOXL3 | |
| SCHEMBL28663602 | 0.76 | SIRT2 (0.44) | LOXL2LOXL3AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311839-B | Methylamine derivatives as lysyl oxidase inhibitors for the treatment of cancer | 癌症研究协会皇家癌症医院 | 2021-11-02 | — | — | CN | disclosed |