Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | NT5E | P21589 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | HSPA8 | P11142 | 4/20 | 0.55 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.55 |
| ▸ | AMD1 | P17707 | 4/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | GAPDH | P04406 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PNP | P00491 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14075808 | 0.88 | HSPA8 (0.57) | LMNAHSPA8HSPA5AMD1RXFP1 | |
| SCHEMBL23982290 | 0.88 | LMNA (0.64) | LMNANT5EHIF1AHSPA8HSPA5 | |
| SCHEMBL18740403 | 0.88 | HSPA8 (0.57) | LMNAHSPA8HSPA5AMD1RXFP1 | |
| SCHEMBL28646728 | 0.86 | LMNA (0.61) | LMNANT5EHIF1AHSPA8HSPA5 | |
| SCHEMBL5034807 | 0.86 | HSPA8 (0.55) | LMNAHSPA8HSPA5AMD1RXFP1 | |
| SCHEMBL5034818 | 0.86 | HSPA8 (0.55) | LMNAHSPA8HSPA5AMD1RXFP1 | |
| SCHEMBL14075810 | 0.86 | HSPA8 (0.55) | LMNAHSPA8HSPA5AMD1RXFP1 | |
| SCHEMBL15906323 | 0.82 | HSPA8 (0.80) | LMNAHSPA8HSPA5AMD1RXFP1 | |
| SCHEMBL13787725 | 0.82 | HSPA8 (0.56) | LMNAHSPA8HSPA5AMD1RXFP1 | |
| SCHEMBL967124 | 0.82 | HSPA8 (0.80) | LMNAHSPA8HSPA5AMD1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113549076-A | Polysubstituted purine compound and preparation method and application thereof | 中国药科大学 | 2021-10-26 | — | — | CN | disclosed |