Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30461169 | 1.00 | ALDH1A1 (0.45) | ALDH1A1HPGDMAPK1MAPTLMNA | |
| SCHEMBL28402413 | 0.89 | ALDH1A1 (0.49) | ALDH1A1HPGDMAPK1MAPTLMNA | |
| SCHEMBL28644066 | 0.87 | LMNA (0.46) | ALDH1A1MAPK1MAPTLMNAUSP2 | |
| SCHEMBL30461179 | 0.80 | FAAH (0.43) | ALDH1A1MAPTLMNAUSP2SMN1; SMN2 | |
| SCHEMBL19305521 | 0.79 | MAPT (0.56) | ALDH1A1HPGDMAPK1MAPTLMNA | |
| SCHEMBL30461173 | 0.79 | MAPT (0.45) | MAPK1MAPTLMNASMN1; SMN2ALOX15 | |
| SCHEMBL28644021 | 0.79 | ALDH1A1 (0.41) | ALDH1A1HPGDMAPK1MAPTLMNA | |
| SCHEMBL30461171 | 0.79 | DRD4 (0.49) | ALDH1A1MAPTLMNAGFERDRD2 | |
| SCHEMBL28661355 | 0.79 | DRD4 (0.49) | ALDH1A1MAPTLMNAGFERDRD2 | |
| SCHEMBL30461178 | 0.79 | ALDH1A1 (0.41) | ALDH1A1HPGDMAPK1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113480485-B | 1,2, 4-triaryl-1, 2, 4-triazoles compound and synthetic method thereof | 甘肃农业大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-113480485-A | 1,2, 4-triaryl-1, 2, 4-triazoles compound and synthetic method thereof | 甘肃农业大学 | 2021-10-08 | — | — | CN | disclosed |