Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | TK1 | P04183 | 5/20 | 0.34 |
| ▸ | TK2 | O00142 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28249876 | 0.86 | TK1 (0.42) | LMNAADRA1ATK1TSHRBLM | |
| SCHEMBL9222586 | 0.80 | LMNA (0.40) | LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL28293120 | 0.78 | LMNA (0.36) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL9227914 | 0.78 | LMNA (0.42) | LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL888124 | 0.76 | TK1 (0.37) | TK1NPSR1 | |
| SCHEMBL28991368 | 0.76 | LMNA (0.36) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL18670742 | 0.76 | P2RY6 (0.38) | TK1 | |
| SCHEMBL2056759 | 0.74 | TK1 (0.39) | LMNATK1TSHRBLMPMP22 | |
| SCHEMBL29854808 | 0.74 | LMNA (0.32) | LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL9343667 | 0.73 | LMNA (0.39) | LMNASMN1; SMN2ALOX12ADRA1ATK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113549121-B | Preparation method of nucleoside modifier | 上海兆维科技发展有限公司 | 2023-05-02 | — | — | CN | claimed |
| CN-113549121-A | Preparation method of nucleoside modifier | 上海兆维科技发展有限公司 | 2021-10-26 | — | — | CN | claimed |
| CN-113549121-B | Preparation method of nucleoside modifier | 上海兆维科技发展有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-113549121-A | Preparation method of nucleoside modifier | 上海兆维科技发展有限公司 | 2021-10-26 | — | — | CN | disclosed |