Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 2/20 | 0.35 |
| ▸ | SELE | P16581 | 2/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.34 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28660920 | 0.81 | LOXL2 (0.42) | LOXL2LOXL3 | |
| SCHEMBL19259684 | 0.80 | LOXL2 (0.34) | LOXL2LOXL3NTRK1 | |
| SCHEMBL19259726 | 0.80 | LOXL2 (0.49) | LOXL2LOXL3 | |
| SCHEMBL28639354 | 0.79 | LOXL2 (0.51) | LOXL2LOXL3 | |
| SCHEMBL28643913 | 0.78 | LOXL2 (0.38) | ICAM1SELELOXL2LOXL3NTRK1 | |
| SCHEMBL28660990 | 0.78 | LOXL2 (0.51) | LOXL2LOXL3NTRK1 | |
| SCHEMBL19259919 | 0.77 | LOXL2 (0.52) | LOXL2 | |
| SCHEMBL28643885 | 0.77 | LOXL3 (0.36) | ICAM1SELELOXL2LOXL3NTRK1 | |
| SCHEMBL28649575 | 0.76 | PDPK1 (0.40) | — | |
| SCHEMBL29970984 | 0.76 | PDPK1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311839-B | Methylamine derivatives as lysyl oxidase inhibitors for the treatment of cancer | 癌症研究协会皇家癌症医院 | 2021-11-02 | — | — | CN | disclosed |