Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.36 |
| ▸ | TUBB | P07437 | 3/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.36 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28643913 | 0.81 | LOXL2 (0.38) | LOXL2LOXL3LMNA | |
| SCHEMBL28639341 | 0.81 | ICAM1 (0.35) | LOXL2LOXL3 | |
| SCHEMBL28643885 | 0.79 | LOXL3 (0.36) | LOXL2SMN1; SMN2LOXL3LMNAALDH1A1 | |
| SCHEMBL19259744 | 0.79 | SMN1; SMN2 (0.41) | LOXL2SMN1; SMN2BRD4ALOX12MAPK10 | |
| SCHEMBL28644238 | 0.78 | LOXL2 (0.41) | LOXL2SMN1; SMN2LOXL3LMNAALDH1A1 | |
| SCHEMBL28651596 | 0.76 | ALDH1A1 (0.42) | LOXL2SMN1; SMN2LOXL3LMNAMAPT | |
| SCHEMBL28663602 | 0.76 | SIRT2 (0.44) | LOXL2SMN1; SMN2LOXL3LMNAMAPT | |
| SCHEMBL19259897 | 0.76 | LOXL2 (0.51) | LOXL2TXKJAK3BTK | |
| SCHEMBL28645865 | 0.75 | LOXL2 (0.40) | LOXL2SMN1; SMN2LOXL3LMNA | |
| SCHEMBL19274587 | 0.75 | PDPK1 (0.41) | LOXL2SMN1; SMN2ALOX12MAPK10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311839-B | Methylamine derivatives as lysyl oxidase inhibitors for the treatment of cancer | 癌症研究协会皇家癌症医院 | 2021-11-02 | — | — | CN | disclosed |