Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29035492 | 0.76 | LMNA (0.34) | LMNANQO1 | |
| SCHEMBL29208120 | 0.76 | SMN1; SMN2 (0.37) | LMNASMN1; SMN2NQO1MAPTL3MBTL1 | |
| SCHEMBL29035247 | 0.75 | HDAC6 (0.33) | LMNA | |
| SCHEMBL28457543 | 0.74 | KDM4E (0.39) | LMNASMN1; SMN2PDK1PDK2PDK3 | |
| SCHEMBL27779427 | 0.73 | MAPK10 (0.34) | SMN1; SMN2MAPK10CCNE1CDK2CDK5 | |
| SCHEMBL20508384 | 0.73 | F2 (0.36) | SMN1; SMN2NQO1CYP1A2CYP3A4MAPT | |
| SCHEMBL21772786 | 0.72 | — | — | |
| SCHEMBL21571637 | 0.71 | CHRM4 (0.38) | FPR2FPR3 | |
| SCHEMBL28644238 | 0.70 | LOXL2 (0.41) | LMNASMN1; SMN2CCNE1CDK2CYP1A2 | |
| SCHEMBL12210734 | 0.70 | SMN1; SMN2 (0.51) | LMNASMN1; SMN2MAPK10CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116437913-A | Pharmaceutical compounds for treating complement-mediated disorders | 艾其林医药公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-109311839-B | Methylamine derivatives as lysyl oxidase inhibitors for the treatment of cancer | 癌症研究协会皇家癌症医院 | 2021-11-02 | — | — | CN | disclosed |