Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29057107 | 0.79 | RAB9A (0.43) | POLBHSD17B10ALOX15SMN1; SMN2ALDH1A1 | |
| SCHEMBL15149636 | 0.74 | F2 (0.64) | F2HSD17B10HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL28639401 | 0.73 | LMNA (0.36) | NQO1SMN1; SMN2CYP1A2CYP3A4MAPT | |
| SCHEMBL20508371 | 0.72 | MGAM (0.50) | HSD17B10ALOX15SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL21812656 | 0.69 | LMNA (0.38) | NQO1ALDH1A1NPC1RAB9ACYP1A2 | |
| SCHEMBL30845136 | 0.68 | FDPS (0.42) | HTTALDH1A1CYP3A4MAPT | |
| SCHEMBL28457543 | 0.67 | KDM4E (0.39) | NQO1SMN1; SMN2ALDH1A1CYP1A2MAPT | |
| SCHEMBL27652396 | 0.65 | MEN1 (0.30) | — | |
| SCHEMBL31227464 | 0.65 | ALDH1A1 (0.47) | POLBHSD17B10SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL20582493 | 0.64 | L3MBTL1 (0.40) | POLBHSD17B10NQO1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3349761-B1 | HEPATITIS B CORE PROTEIN MODULATORS | ASSEMBLY BIOSCIENCES INC (US) | 2022-01-26 | — | — | EP | disclosed |
| US-10392379-B2 | Hepatitis B core protein modulators | ASSEMBLY BIOSCIENCES, INC. (US) | 2019-08-27 | — | — | US | disclosed |
| US-20180273520-A1 | HEPATITIS B CORE PROTEIN MODULATORS | Assembly Bioscience, Inc. (US) | 2018-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10392379-B2 | Hepatitis B core protein modulators | HAVCR2, FABP1, MAVS | F2 2930/4885POLB 1965/4885HSD17B10 2051/4885 |
| US-20180273520-A1 | HEPATITIS B CORE PROTEIN MODULATORS | HAVCR2, FABP1, MAVS | F2 2930/4885POLB 1965/4885HSD17B10 2051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.