Known targets — ChEMBL curated mechanism
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The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | HBB | P68871 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL2039900 | 1.00 | TSHR (0.50) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL28240025 | 0.96 | TSHR (0.53) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL21599246 | 0.92 | TSHR (0.50) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL21801676 | 0.92 | TSHR (0.50) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL4303342 | 0.92 | TSHR (0.50) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL25333131 | 0.92 | TSHR (0.50) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL21409712 | 0.92 | TSHR (0.50) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL21808784 | 0.92 | — | — | |
| Alcohol SCHEMBL25399402 | 0.92 | TSHR (0.50) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL21297005 | 0.92 | TSHR (0.60) | TSHRALDH1A1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113559930-A | Preparation method and application of solid catalyst taking sodium lignosulfonate as carrier | 南京林业大学 | 2021-10-29 | — | — | CN | disclosed |