6-Methoxyflavone

6-Methoxyflavone

SCHEMBL30799564

COc1ccc2oc(-c3ccccc3)cc(=O)c2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 1/20 1.00
ABCG2 Q9UNQ0 1/20 1.00
KDM4E B2RXH2 6/20 0.83
ALDH1A1 P00352 6/20 0.83
MAPT P10636 6/20 0.83
CYP3A4 P08684 5/20 0.83
HPGD P15428 5/20 0.83
TP53 P04637 4/20 0.83
HSD17B10 Q99714 4/20 0.83
NPC1 O15118 4/20 0.83
RAB9A P51151 4/20 0.83
SMN1; SMN2 Q16637 3/20 0.83
LMNA P02545 2/20 0.83
THRB P10828 2/20 0.83
NFKB1 P19838 2/20 0.83
NFKB2 Q00653 2/20 0.83
RELA Q04206 2/20 0.83
RXFP1 Q9HBX9 1/20 0.83
TNKS O95271 2/20 0.81
CYP19A1 P11511 1/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
6-Methoxyflavone SCHEMBL312059 1.00 ABCB1 (1.00) ABCB1ABCG2KDM4EALDH1A1MAPT
6-Methoxyflavone SCHEMBL28930176 1.00 ABCB1 (1.00) ABCB1ABCG2KDM4EALDH1A1MAPT
6-Methoxyflavone SCHEMBL28301080 0.99 ABCB1 (0.97) ABCB1ABCG2KDM4EALDH1A1MAPT
6-Methoxyflavone SCHEMBL27697051 0.96 ABCB1 (0.92) ABCB1ABCG2KDM4EALDH1A1MAPT
SCHEMBL31238446 0.92 ABCB1 (0.85) ABCB1ABCG2KDM4EALDH1A1MAPT
6,4'-Dimethoxyflavone SCHEMBL4281291 0.91 MAPT (1.00) ABCB1ABCG2KDM4EALDH1A1MAPT
6,4'-Dimethoxyflavone SCHEMBL29478471 0.91 MAPT (1.00) ABCB1ABCG2KDM4EALDH1A1MAPT
6,3'-Dimethoxyflavone SCHEMBL30894690 0.90 KDM4E (0.82) ABCB1ABCG2KDM4EALDH1A1MAPT
6,3'-Dimethoxyflavone SCHEMBL516389 0.90 KDM4E (0.82) ABCB1ABCG2KDM4EALDH1A1MAPT
7-Methoxyflavone SCHEMBL1373009 0.90 TNKS (1.00) ABCB1ABCG2KDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4331564-A1 ANTIOXIDANT COMPOSITION COMPRISING 5-DEOXYFLAVONOIDS Analyticon Discovery GmbH (DE) 2024-03-06 EP disclosed