6-Methoxyflavone

6-Methoxyflavone

SCHEMBL312059

COc1ccc2oc(-c3ccccc3)cc(=O)c2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 1/20 1.00
ABCG2 Q9UNQ0 1/20 1.00
KDM4E B2RXH2 6/20 0.83
ALDH1A1 P00352 6/20 0.83
MAPT P10636 6/20 0.83
CYP3A4 P08684 5/20 0.83
HPGD P15428 5/20 0.83
TP53 P04637 4/20 0.83
HSD17B10 Q99714 4/20 0.83
NPC1 O15118 4/20 0.83
RAB9A P51151 4/20 0.83
SMN1; SMN2 Q16637 3/20 0.83
LMNA P02545 2/20 0.83
THRB P10828 2/20 0.83
NFKB1 P19838 2/20 0.83
NFKB2 Q00653 2/20 0.83
RELA Q04206 2/20 0.83
RXFP1 Q9HBX9 1/20 0.83
TNKS O95271 2/20 0.81
CYP19A1 P11511 1/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
6-Methoxyflavone SCHEMBL28930176 1.00 ABCB1 (1.00) ABCB1ABCG2KDM4EALDH1A1MAPT
6-Methoxyflavone SCHEMBL30799564 1.00 ABCB1 (1.00) ABCB1ABCG2KDM4EALDH1A1MAPT
6-Methoxyflavone SCHEMBL28301080 0.99 ABCB1 (0.97) ABCB1ABCG2KDM4EALDH1A1MAPT
6-Methoxyflavone SCHEMBL27697051 0.96 ABCB1 (0.92) ABCB1ABCG2KDM4EALDH1A1MAPT
SCHEMBL31238446 0.92 ABCB1 (0.85) ABCB1ABCG2KDM4EALDH1A1MAPT
6,4'-Dimethoxyflavone SCHEMBL4281291 0.91 MAPT (1.00) ABCB1ABCG2KDM4EALDH1A1MAPT
6,4'-Dimethoxyflavone SCHEMBL29478471 0.91 MAPT (1.00) ABCB1ABCG2KDM4EALDH1A1MAPT
6,3'-Dimethoxyflavone SCHEMBL30894690 0.90 KDM4E (0.82) ABCB1ABCG2KDM4EALDH1A1MAPT
6,3'-Dimethoxyflavone SCHEMBL516389 0.90 KDM4E (0.82) ABCB1ABCG2KDM4EALDH1A1MAPT
7-Methoxyflavone SCHEMBL1373009 0.90 TNKS (1.00) ABCB1ABCG2KDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119470756-A UPLC quantitative fingerprint detection method for camphor head red tangerine peel 赣江中药创新中心 2025-02-18 CN claimed
CN-118102892-A Composition comprising a nutrient and a taste modifier 弗门尼舍有限公司 2024-05-28 CN claimed
CN-117250298-A Construction method of liquid fingerprint of agilawood and fingerprint thereof 中国中医科学院中药研究所 2023-12-19 CN claimed
CN-113512018-B Flavonoid compound and preparation method and application thereof 合肥工业大学 2023-07-18 CN claimed
CN-101370470-B C-KIT activation inhibitor, skin whitening compound and composition for skin whitening containing the same LG HOUSEHOLD & HEALTH CARE LTD 2012-04-11 CN claimed
CN-101370470-A C-KIT activation inhibitor, skin whitening compound and composition for skin whitening containing the same LG HOUSEHOLD & HEALTH CARE LTD (KR) 2009-02-18 CN claimed
WO-2007083904-A1 C-KIT ACTIVATION INHIBITOR, SKIN WHITENING COMPOUND AND COMPOSITION FOR SKIN WHITENING CONTAINING THE SAME LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2007-07-26 WO claimed
US-6872771-B1 Tire with rubber containing flavone THE GOODYEAR TIRE & RUBBER COMPANY (US) 2005-03-29 US claimed
JP-2003504327-A 2003-02-04 JP claimed
EP-1223928-A2 USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS Prendergast, Patrick Thomas (IE) 2002-07-24 EP claimed
WO-2001003681-A2 USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS PRENDERGAST PATRICK T (IE) 2001-01-18 WO claimed
WO-1996031206-A2 FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS WARNER-LAMBERT COMPANY (US) 1996-10-10 WO claimed
CN-122028804-A Flavanone compounds and their use as flavor modifiers 弗门尼舍有限公司 2026-05-12 CN disclosed
US-12368049-B2 Protective film agent and processing method of workpiece DISCO CORPORATION (JP) 2025-07-22 US disclosed
EP-4580594-A1 ANTIOXIDANT COMPOSITION COMPRISING 5-DEOXYFLAVONOIDS AnalytiCon Discovery - Zweigniederlassung der BRAIN Biotech AG (DE) 2025-07-09 EP disclosed
CN-119031856-A Fatty acid amides and their use as flavor modifiers 弗门尼舍有限公司 2024-11-26 CN disclosed
EP-1096930-A1 THERAPEUTIC COMPOSITION BASED ON FLAVONOIDS FOR USE IN THE TREATMENT OF TUMOURS WITH CYTOTOXIC AGENTS LABORATOIRE L. LAFON (FR) 2001-05-09 EP disclosed
WO-2001003681-A2 USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS PRENDERGAST PATRICK T (IE) 2001-01-18 WO disclosed
WO-2000003706-A1 THERAPEUTIC COMPOSITION BASED ON FLAVONOIDS FOR USE IN THE TREATMENT OF TUMOURS WITH CYTOTOXIC AGENTS LABORATOIRE L. LAFON (FR) 2000-01-27 WO disclosed
WO-1996031206-A2 FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS WARNER-LAMBERT COMPANY (US) 1996-10-10 WO disclosed