Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 3/20 | 0.50 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.50 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL28639836 | 1.00 | GABRR1 (0.50) | GABRR1GABBR2GABBR1ANPEPERAP2 | |
| SCHEMBL18973928 | 0.86 | — | — | |
| SCHEMBL5217527 | 0.86 | — | — | |
| SCHEMBL1603964 | 0.86 | — | — | |
| Phosphoric Acid SCHEMBL3835102 | 0.83 | CA1 (0.45) | GABRR1GABBR2GABBR1CA1CA2 | |
| Hydrochloric Acid SCHEMBL2599287 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL933615 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL932735 | 0.83 | — | — | |
| SCHEMBL1400213 | 0.77 | TSHR (0.48) | GABRR1GABBR2GABBR1LMNACA1 | |
| Phosphoric Acid SCHEMBL7136276 | 0.76 | GABRR1 (0.52) | GABRR1GABBR2GABBR1ANPEPERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113600097-B | Preparation method of asymmetric gemini imidazoline phosphate surfactant | 上海发凯化工有限公司 | 2023-02-14 | — | — | CN | claimed |
| CN-113600097-A | Preparation method of asymmetric gemini imidazoline phosphate surfactant | 上海发凯化工有限公司 | 2021-11-05 | — | — | CN | claimed |
| CN-113600097-B | Preparation method of asymmetric gemini imidazoline phosphate surfactant | 上海发凯化工有限公司 | 2023-02-14 | — | — | CN | disclosed |
| CN-113600097-B | Preparation method of asymmetric gemini imidazoline phosphate surfactant | 上海发凯化工有限公司 | 2023-02-14 | — | — | CN | disclosed |
| CN-113600097-A | Preparation method of asymmetric gemini imidazoline phosphate surfactant | 上海发凯化工有限公司 | 2021-11-05 | — | — | CN | disclosed |
| CN-113600097-A | Preparation method of asymmetric gemini imidazoline phosphate surfactant | 上海发凯化工有限公司 | 2021-11-05 | — | — | CN | disclosed |