Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 7/20 | 0.38 |
| ▸ | JAK1 | P23458 | 6/20 | 0.38 |
| ▸ | JAK2 | O60674 | 5/20 | 0.38 |
| ▸ | TYK2 | P29597 | 3/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 8/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.34 |
| ▸ | SYK | P43405 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28639475 | 0.84 | PRKCQ (0.41) | JAK3JAK1JAK2TYK2MAPK8 | |
| SCHEMBL19665710 | 0.81 | MAPK8 (0.45) | MAPK8MAPK9SYK | |
| SCHEMBL19665717 | 0.81 | JAK1 (0.37) | JAK3JAK1JAK2TYK2MAPK8 | |
| SCHEMBL29802436 | 0.80 | STK17B (0.37) | JAK3JAK1JAK2TYK2MAPK8 | |
| SCHEMBL28652855 | 0.80 | JAK3 (0.38) | JAK3JAK1JAK2TYK2MAPK8 | |
| SCHEMBL29290164 | 0.78 | JAK2 (0.34) | JAK3JAK1JAK2TYK2MAPK8 | |
| SCHEMBL19665711 | 0.77 | MAPK8 (0.38) | JAK3JAK1JAK2MAPK8MAPK9 | |
| SCHEMBL19665693 | 0.74 | SIRT5 (0.41) | MAPK8MAPK9ADORA3MAPK10 | |
| SCHEMBL19665726 | 0.73 | STK17B (0.56) | — | |
| SCHEMBL29802472 | 0.73 | STK17B (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563095-B | Animal and human antimalarial agents | 细胞基因公司 | 2021-10-29 | — | — | CN | disclosed |