Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 12/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | TYK2 | P29597 | 2/20 | 0.35 |
| ▸ | JAK3 | P52333 | 2/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28639902 | 0.84 | JAK3 (0.38) | JAK2TYK2JAK3JAK1MAPK8 | |
| SCHEMBL19665564 | 0.83 | L3MBTL1 (0.44) | PRKCQL3MBTL1STK17AMAPT | |
| SCHEMBL28644319 | 0.83 | PRKCQ (0.44) | PRKCQL3MBTL1GSK3AGSK3BCDK2 | |
| SCHEMBL28657267 | 0.82 | L3MBTL1 (0.47) | PRKCQL3MBTL1STK17ASIRT5PTK2B | |
| SCHEMBL19665753 | 0.82 | PRKCQ (0.42) | PRKCQL3MBTL1STK17ASIRT5PTK2B | |
| SCHEMBL29802501 | 0.80 | PRKCQ (0.38) | PRKCQL3MBTL1STK17ASIRT5PTK2B | |
| SCHEMBL19665748 | 0.79 | PRKCQ (0.43) | PRKCQL3MBTL1STK17APTK2BMEN1 | |
| SCHEMBL19665714 | 0.76 | SIRT5 (0.53) | PRKCQL3MBTL1STK17ASIRT5PTK2B | |
| SCHEMBL19665633 | 0.75 | STK17A (0.53) | PRKCQL3MBTL1STK17ASIRT5PTK2B | |
| SCHEMBL28650009 | 0.75 | PIN1 (0.44) | PRKCQL3MBTL1STK17APTK2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563095-B | Animal and human antimalarial agents | 细胞基因公司 | 2021-10-29 | — | — | CN | disclosed |