Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 8/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | HNF4A | P41235 | 2/20 | 0.33 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28637205 | 0.77 | MAPT (0.49) | FTOIDO1CYP3A4CSF1RFNTA | |
| SCHEMBL28636872 | 0.73 | FTO (0.44) | FTOIDO1CYP3A4CSF1RFNTA | |
| SCHEMBL28926573 | 0.73 | FTO (0.44) | FTOIDO1CYP3A4CSF1RFNTA | |
| SCHEMBL21857697 | 0.65 | IDO1 (0.54) | FTOIDO1CYP3A4PARP1HPGDS | |
| Benzene SCHEMBL27914219 | 0.64 | BCAT2 (0.50) | MKNK1HNF4AACMSD | |
| SCHEMBL28475228 | 0.64 | BCAT2 (0.50) | MKNK1HNF4AACMSD | |
| SCHEMBL27639675 | 0.64 | BCAT2 (0.50) | MKNK1HNF4AACMSD | |
| SCHEMBL28353064 | 0.64 | BCAT2 (0.50) | MKNK1HNF4AACMSD | |
| SCHEMBL27323238 | 0.64 | IDO1 (0.59) | FTOIDO1CYP3A4PARP1 | |
| SCHEMBL2417930 | 0.63 | IDO1 (0.45) | IDO1CYP3A4CSF1RHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113396145-A | PFKFB3 inhibitors and uses thereof | 盖罗发现有限责任公司 | 2021-09-14 | — | — | CN | disclosed |