Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 2/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | CTSH | P09668 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3408683 | 0.89 | TSHR (0.31) | — | |
| SCHEMBL19405399 | 0.85 | — | — | |
| SCHEMBL19405505 | 0.85 | — | — | |
| SCHEMBL19405436 | 0.85 | — | — | |
| SCHEMBL1071095 | 0.82 | TRPA1 (0.32) | — | |
| SCHEMBL340706 | 0.81 | ALDH1A1 (0.41) | BDKRB2 | |
| SCHEMBL3669480 | 0.80 | PRSS1 (0.38) | BDKRB2CSNK1ECNR2 | |
| SCHEMBL5207741 | 0.79 | ACE2 (0.37) | CSNK1ECNR2 | |
| SCHEMBL3676969 | 0.78 | PRSS1 (0.39) | CSNK1ECNR2 | |
| SCHEMBL3677339 | 0.78 | PRSS1 (0.39) | CSNK1ECNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105980386-B | Pyrazolo compounds and uses thereof | 基因泰克公司 | 2021-08-13 | — | — | CN | disclosed |