SCHEMBL2864134

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4361356	0.95	MEN1 (0.59)	RAB9AMEN1KMT2ASIRT2SIRT1
	SCHEMBL2865568	0.89	SIRT2 (0.52)	RAB9AMEN1KMT2ASIRT2SIRT1
	SCHEMBL2871426	0.86	RAB9A (0.49)	RAB9AMEN1KMT2ASIRT2SIRT1
	SCHEMBL2870953	0.86	MEN1 (0.55)	RAB9AMEN1KMT2ASIRT2SIRT1
	SCHEMBL13956823	0.85	NPC1 (0.56)	RAB9AMEN1KMT2ASIRT2SIRT1
	SCHEMBL2868677	0.84	ALDH1A1 (0.63)	RAB9AMEN1KMT2AALDH1A1MAPT
	SCHEMBL2857191	0.81	RAB9A (0.65)	RAB9AMEN1KMT2AALDH1A1MAPT
	SCHEMBL2869227	0.81	NPC1 (0.56)	RAB9AMEN1KMT2ASIRT2SIRT1
	SCHEMBL27690733	0.79	KDM4E (0.47)	RAB9AMEN1KMT2ASIRT2SIRT1
	SCHEMBL4365508	0.78	MEN1 (0.61)	RAB9AMEN1KMT2ASIRT2SIRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.