SCHEMBL2864152

SCHEMBL2864152

CC1=CC([Zr](Cl)(Cl)(=C(c2ccccc2)c2ccccc2)C2c3cc(C(C)(C)C)ccc3-c3ccc(C(C)(C)C)cc32)c2cc(C)ccc21

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KCNK3 O14649 1/20 0.30
LMNA P02545 1/20 0.30
KCNK9 Q9NPC2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2866152 0.94 KCNK3 (0.31) KCNK3KCNK9
SCHEMBL2868592 0.93 NPC1 (0.32) LMNAKCNK9
SCHEMBL2861631 0.92 NPC1 (0.33)
SCHEMBL2867900 0.88 NPC1 (0.32) LMNA
SCHEMBL2863298 0.88 NPC1 (0.32) LMNA
SCHEMBL2871024 0.85 NPC1 (0.32)
SCHEMBL2866135 0.85
SCHEMBL2860945 0.85 ALDH1A1 (0.31) LMNAKCNK9
SCHEMBL2860436 0.85 LMNA (0.31) LMNAKCNK9
SCHEMBL2868911 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7838611-B2 Ethylene polymer, catalyst for ethylene polymer production, and method for producing ethylene polymer TOSOH CORPORATION (JP) 2010-11-23 US disclosed
US-7678866-B2 Polyethylene composition and process for producing same TOSOH CORPORATION (JP) 2010-03-16 US disclosed
US-20090137755-A1 ETHYLENE POLYMER, CATALYST FOR ETHYLENE POLYMER PRODUCTION, AND METHOD FOR PRODUCING ETHYLENE POLYMER TOSOH CORPORATION (JP) 2009-05-28 US disclosed
US-20040214953-A1 Polyethylene composition and process for producing same TOSOH CORPORATION 2004-10-28 US disclosed