Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 12/20 | 0.57 |
| ▸ | RAB9A | P51151 | 12/20 | 0.57 |
| ▸ | PKM | P14618 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | KLF5 | Q13887 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | SCD | O00767 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17488078 | 0.92 | NPC1 (0.68) | NPC1RAB9APKMSMN1; SMN2ADORA2A | |
| SCHEMBL5744081 | 0.92 | NPC1 (0.70) | NPC1RAB9APKMSMN1; SMN2ADORA2A | |
| SCHEMBL15224049 | 0.89 | RAB9A (0.54) | NPC1RAB9APKMSMN1; SMN2ADORA2A | |
| SCHEMBL28642016 | 0.89 | NPC1 (0.57) | NPC1RAB9APKMSMN1; SMN2ADORA2A | |
| SCHEMBL12392436 | 0.86 | RAB9A (0.51) | NPC1RAB9APKMSMN1; SMN2ADORA2A | |
| SCHEMBL16562173 | 0.86 | NPC1 (0.78) | NPC1RAB9APKMSMN1; SMN2ADORA2A | |
| SCHEMBL5355854 | 0.82 | LMNA (0.63) | NPC1RAB9APKMSMN1; SMN2ADORA2A | |
| SCHEMBL11706151 | 0.81 | NPC1 (0.72) | NPC1RAB9APKMSMN1; SMN2ADORA2A | |
| SCHEMBL5744080 | 0.81 | NPC1 (0.70) | NPC1RAB9APKMSMN1; SMN2ADORA2A | |
| SCHEMBL5351438 | 0.80 | LMNA (0.53) | NPC1SMN1; SMN2ADORA2ATP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110577642-B | Acyl-containing benzimidazole polyimide, preparation method thereof, acyl-containing benzimidazole polyimide film, preparation method and application | 东华大学 | 2021-10-19 | — | — | CN | disclosed |
| CN-110577642-A | acyl-containing benzimidazole polyimide, preparation method thereof, acyl-containing benzimidazole polyimide film, preparation method and application | 东华大学 | 2019-12-17 | — | — | CN | disclosed |