Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | ITK | Q08881 | 4/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | PRKCG | P05129 | 1/20 | 0.46 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.46 |
| ▸ | MARK3 | P27448 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30533209 | 1.00 | NPC1 (0.58) | NPC1RAB9APDE11APDE10ASMN1; SMN2 | |
| SCHEMBL15223910 | 0.91 | NPC1 (0.54) | NPC1RAB9APDE11APDE10ASMN1; SMN2 | |
| SCHEMBL12392471 | 0.87 | NPC1 (0.51) | NPC1RAB9APDE11APDE10ASMN1; SMN2 | |
| SCHEMBL28652762 | 0.81 | ALDH1A1 (0.53) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL209641 | 0.76 | KDM4E (0.46) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL5038741 | 0.76 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL28886322 | 0.74 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL5349165 | 0.74 | BRAF (0.49) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL16329710 | 0.74 | NAMPT (0.55) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL5032471 | 0.74 | RAB9A (0.55) | NPC1RAB9ASMN1; SMN2ITKIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116444794-A | Benzimidazolyl-containing polyimide, and preparation method and application thereof | 中广核研究院有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-110577642-B | Acyl-containing benzimidazole polyimide, preparation method thereof, acyl-containing benzimidazole polyimide film, preparation method and application | 东华大学 | 2021-10-19 | — | — | CN | disclosed |
| CN-110577495-A | amide-containing N-substituted benzimidazole diamine and preparation method thereof | 东华大学 | 2019-12-17 | — | — | CN | disclosed |
| CN-110577642-A | acyl-containing benzimidazole polyimide, preparation method thereof, acyl-containing benzimidazole polyimide film, preparation method and application | 东华大学 | 2019-12-17 | — | — | CN | disclosed |