Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.55 |
| ▸ | NPC1 | O15118 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MMP2 | P08253 | 2/20 | 0.53 |
| ▸ | MMP9 | P14780 | 2/20 | 0.53 |
| ▸ | MMP8 | P22894 | 2/20 | 0.53 |
| ▸ | MMP13 | P45452 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ITK | Q08881 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28958918 | 0.76 | RAB9A (0.62) | RAB9ANPC1KMT2AMAPTMEN1 | |
| SCHEMBL130860 | 0.76 | KDM4E (0.57) | RAB9ANPC1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL13594627 | 0.74 | IRAK4 (0.76) | ITKIRAK4 | |
| SCHEMBL28642017 | 0.74 | NPC1 (0.58) | RAB9ANPC1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL30533209 | 0.74 | NPC1 (0.58) | RAB9ANPC1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL4976545 | 0.73 | NPC1 (0.50) | RAB9ANPC1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL31474751 | 0.72 | HTT (0.71) | RAB9ANPC1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL5097531 | 0.72 | IRAK4 (0.69) | ITKIRAK4 | |
| SCHEMBL14075220 | 0.72 | MEN1 (0.71) | KMT2AHTTSMN1; SMN2MAPTMEN1 | |
| SCHEMBL209281 | 0.72 | ALDH1A1 (0.54) | RAB9ANPC1KMT2AHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534275-B1 | ACYLAMINO-SUBSTITUTED HETEROAROMATIC COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2008-03-12 | — | — | EP | disclosed |