Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 7/20 | 0.34 |
| ▸ | DRD2 | P14416 | 6/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | ALB | P02768 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28642986 | 0.82 | SLC18A3 (0.36) | TSHR | |
| SCHEMBL12326822 | 0.76 | HTR2C (0.38) | EGLN2DRD3DRD2CYP2D6TSHR | |
| SCHEMBL25908579 | 0.73 | HTR2C (0.35) | DRD3DRD2ALDH1A1MAPTNPSR1 | |
| SCHEMBL29672154 | 0.72 | TRPM5 (0.39) | EGLN2DRD3DRD2 | |
| SCHEMBL1978879 | 0.72 | MEN1 (0.38) | EGLN2DRD3DRD2CYP2D6TSHR | |
| SCHEMBL24690097 | 0.72 | EGLN2 (0.37) | EGLN2DRD3DRD2SLC6A4CYP2D6 | |
| SCHEMBL16954813 | 0.72 | EGLN2 (0.37) | EGLN2DRD3DRD2CYP2D6TSHR | |
| SCHEMBL16961551 | 0.72 | EGLN2 (0.37) | EGLN2DRD3DRD2CYP2D6TSHR | |
| SCHEMBL16959366 | 0.72 | DRD2 (0.40) | EGLN2DRD3DRD2CYP2D6TSHR | |
| SCHEMBL16953765 | 0.71 | EGLN2 (0.35) | EGLN2DRD3DRD2GRIA1GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020117877-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE | AQUINNAH PHARMACEUTICALS, INC. (US) | 2020-06-11 | — | — | WO | disclosed |