Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 5/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.49 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.49 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.48 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.48 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.48 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.48 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.48 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.48 |
| ▸ | PREP | P48147 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16256993 | 0.91 | AGTR2 (0.51) | AGTR2HTR2CNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL221540 | 0.87 | PREP (0.55) | NPC1RAB9ASMN1; SMN2PREPACE2 | |
| SCHEMBL221538 | 0.87 | PREP (0.55) | NPC1RAB9ASMN1; SMN2PREPACE2 | |
| SCHEMBL221539 | 0.87 | PREP (0.55) | NPC1RAB9ASMN1; SMN2PREPACE2 | |
| SCHEMBL29302842 | 0.86 | SMN1; SMN2 (0.56) | AGTR2HTR2CNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5740609 | 0.86 | SMN1; SMN2 (0.56) | AGTR2HTR2CNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29302825 | 0.86 | SMN1; SMN2 (0.56) | AGTR2HTR2CNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16361631 | 0.86 | AGTR2 (0.47) | AGTR2HTR2CNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20146333 | 0.85 | PDK1 (0.50) | AGTR2HTR2CNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22038874 | 0.85 | HTR2C (0.56) | HTR2CNPC1RAB9ASMN1; SMN2PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107709337-B | Process for the preparation of 7H-pyrrolo [2, 3-d ] pyrimidine derivatives and intermediates therefor | 日本烟草产业株式会社 | 2021-11-16 | — | — | CN | disclosed |