Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9058058 | 0.79 | KDM4E (0.50) | KDM4EMAPTHSP90AA1HTTTP53 | |
| SCHEMBL31330058 | 0.71 | KDM4E (0.44) | KDM4EMAPTHSP90AA1HTTTP53 | |
| SCHEMBL30895368 | 0.70 | GPR3 (0.56) | KDM4EMAPTHSP90AA1HTTTP53 | |
| SCHEMBL11199602 | 0.70 | GPR3 (0.56) | KDM4EMAPTHSP90AA1HTTTP53 | |
| SCHEMBL11222044 | 0.68 | HSP90AA1 (0.45) | KDM4EMAPTHSP90AA1HTTTP53 | |
| SCHEMBL31330029 | 0.68 | MEN1 (0.44) | KDM4EMAPTHSP90AA1HTTTP53 | |
| SCHEMBL14358282 | 0.68 | KDM4E (0.42) | KDM4EMAPTHSP90AA1HTTTP53 | |
| SCHEMBL1702822 | 0.67 | GPR3 (0.59) | KDM4EMAPTHTTTP53SMN1; SMN2 | |
| SCHEMBL1311427 | 0.66 | PARP1 (0.39) | KDM4EMAPTHSP90AA1HTTTP53 | |
| SCHEMBL498829 | 0.66 | HSP90AA1 (0.58) | KDM4EMAPTHSP90AA1HTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423430-A | Amanitoxin conjugates containing branched linkers | 杭州多禧生物科技有限公司 | 2021-09-21 | — | — | CN | disclosed |