Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 3/20 | 0.39 |
| ▸ | CCR8 | P51685 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30895368 | 0.84 | GPR3 (0.56) | HSP90AA1L3MBTL1NPC1KDM4EMAPT | |
| SCHEMBL11199602 | 0.84 | GPR3 (0.56) | HSP90AA1L3MBTL1NPC1KDM4EMAPT | |
| SCHEMBL9058058 | 0.81 | KDM4E (0.50) | HSP90AA1L3MBTL1NPC1KDM4EMAPT | |
| SCHEMBL11195631 | 0.81 | MAPT (0.57) | HSP90AA1L3MBTL1NPC1KDM4EMAPT | |
| SCHEMBL11203305 | 0.80 | GPR3 (0.64) | HSP90AA1L3MBTL1NPC1KDM4EMAPT | |
| SCHEMBL29211321 | 0.77 | KDM4E (0.43) | HSP90AA1L3MBTL1NPC1KDM4EMAPT | |
| SCHEMBL30373152 | 0.75 | LMNA (0.42) | HSP90AA1L3MBTL1NPC1KDM4EMAPT | |
| SCHEMBL19233003 | 0.71 | DHFR (0.53) | HSP90AA1L3MBTL1NPC1KDM4EMAPT | |
| SCHEMBL29408294 | 0.71 | ALDH1A1 (0.55) | HSP90AA1NPC1KDM4EMAPTLMNA | |
| SCHEMBL88611 | 0.71 | ALDH1A1 (0.55) | HSP90AA1NPC1KDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4369318-A | USING A BENZO-OR PYRIDO-CINNOLINES AS BLEACH CATALYST | CIBA-GEIGY LTD. (CH) | 1983-01-18 | — | — | US | disclosed |
| US-4266011-A | FUSED PYRIDAZINE CATALYST | CIBA-GEIGY AG (CH) | 1981-05-05 | — | — | US | disclosed |