Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | CCR1 | P32246 | 4/20 | 0.50 |
| ▸ | CCR8 | P51685 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CCR5 | P51681 | 3/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30895368 | 0.83 | GPR3 (0.56) | KDM4ECCR1CCR8LMNAMAPT | |
| SCHEMBL11199602 | 0.83 | GPR3 (0.56) | KDM4ECCR1CCR8LMNAMAPT | |
| SCHEMBL11222044 | 0.81 | HSP90AA1 (0.45) | KDM4ECCR1CCR8LMNAMAPT | |
| SCHEMBL16626082 | 0.79 | HSP90AA1 (0.43) | KDM4ECCR1CCR8LMNAMAPT | |
| SCHEMBL28644683 | 0.79 | KDM4E (0.38) | KDM4ECCR1CCR8LMNAMAPT | |
| SCHEMBL22792600 | 0.78 | HSP90AA1 (0.34) | KDM4ECCR1CCR8LMNAMAPT | |
| SCHEMBL21657800 | 0.78 | HSP90AA1 (0.42) | KDM4ECCR1CCR8LMNAMAPT | |
| SCHEMBL16626083 | 0.78 | PRMT5 (0.49) | KDM4ECCR1CCR8LMNAMAPT | |
| SCHEMBL14314008 | 0.75 | PDE4A (0.38) | KDM4ECCR1CCR8LMNAMAPT | |
| SCHEMBL8194 | 0.74 | ALDH1A1 (0.67) | KDM4ECCR1CCR8LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151020-A1 | HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE | WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) | 2023-05-18 | — | — | US | disclosed |
| US-20230151020-A1 | HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE | WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) | 2023-05-18 | — | — | US | disclosed |
| US-10406227-B2 | Photoactivated molecules for light-induced modulation of the activity of electrically excitable cells and methods of using same | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2019-09-10 | — | — | US | disclosed |
| EP-3027229-B1 | PHOTOACTIVATED MOLECULES FOR LIGHT-INDUCED MODULATION OF THE ACTIVITY OF ELECTRICALLY EXCITABLE CELLS AND METHODS OF USING SAME | UNIV SOUTHERN CALIFORNIA (US) | 2019-07-17 | — | — | EP | disclosed |
| US-10232043-B2 | Photoactivated molecules for light-induced modulation of the activity of electrically excitable cells and methods of using the same | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2019-03-19 | — | — | US | disclosed |
| US-20170189530-A1 | PHOTOACTIVATED MOLECULES FOR LIGHT INDUCED MODULATION OF THE ACTIVITY OF ELECTRICALLY EXCITABLE CELLS AND METHODS OF USING THE SAME | UNIVERSITY OF SOUTHERN CALIFORNIA | 2017-07-06 | — | — | US | disclosed |
| WO-2017031380-A1 | PHOTOACTIVATED MOLECULES FOR LIGHT-INDUCED MODULATION OF THE ACTIVITY OF ELECTRICALLY EXCITABLE CELLS AND METHODS OF USING | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2017-02-23 | — | — | WO | disclosed |
| EP-3027229-A1 | PHOTOACTIVATED MOLECULES FOR LIGHT-INDUCED MODULATION OF THE ACTIVITY OF ELECTRICALLY EXCITABLE CELLS AND METHODS OF USING SAME | University of Southern California (US) | 2016-06-08 | — | — | EP | disclosed |
| US-20150328313-A1 | PHOTOACTIVATED MOLECULES FOR LIGHT-INDUCED MODULATION OF THE ACTIVITY OF ELECTRICALLY EXCITABLE CELLS AND METHODS OF USING SAME | UNIVERSITY OF SOUTHERN CALIFORNIA | 2015-11-19 | — | — | US | disclosed |
| WO-2014100283-A1 | PHOTOACTIVATED MOLECULES FOR LIGHT-INDUCED MODULATION OF THE ACTIVITY OF ELECTRICALLY EXCITABLE CELLS AND METHODS OF USING SAME | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2014-06-26 | — | — | WO | disclosed |
| EP-0486103-B1 | Polymers of carbon monoxide with styrene | SHELL INT RESEARCH (NL) | 1996-10-02 | — | — | EP | disclosed |
| EP-0486103-A2 | Polymers of carbon monoxide with styrene | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-05-20 | — | — | EP | disclosed |
| US-4369318-A | USING A BENZO-OR PYRIDO-CINNOLINES AS BLEACH CATALYST | CIBA-GEIGY LTD. (CH) | 1983-01-18 | — | — | US | disclosed |
| US-4266011-A | FUSED PYRIDAZINE CATALYST | CIBA-GEIGY AG (CH) | 1981-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10406227-B2 | Photoactivated molecules for light-induced modulation of the activity of electrically excitable cells and methods of using same | TRPM8, TRPM2, TRPM4 | KDM4E 2848/4885CCR1 4487/4885CCR8 4160/4885 |
| US-20230151020-A1 | HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE | OCIAD1, OCIAD2, EHD1 | KDM4E 2555/4885CCR1 3282/4885CCR8 4107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.